Ferimax 200 mg/10 ml (IV Injection or Infusion)

10 ml ampoule: ৳ 600.00

Medicine Details

Category	Details
Generic	Iron sucrose
Company	Incepta pharmaceuticals ltd
Also available as	Ferimax 100 mg injection Ferimax 50 mg injection

Indications

Treatment of Ferimax deficiency in various medical conditions
Rapid Ferimax supply in clinical need
Patients intolerant to oral Ferimax therapy
Patients with active inflammatory bowel disease
Non-dialysis dependent-chronic kidney disease patients
Hemodialysis dependent-chronic kidney disease patients
Peritoneal dialysis dependent-chronic kidney disease patients
Treatment of Ferimax deficiency in surgical patients
Treatment of Ferimax deficiency in blood donors
Treatment of Ferimax deficiency in postpartum patients

Pharmacology

Iron Sucrose Injection USP is a brown, sterile, aqueous, complex of Polynuclear Iron (III) Hydroxide in Sucrose for Intravenous use. It contains approximately 30% Sucrose w/v and has a pH of 10..5-11.1. It is dissociated into Iron and Sucrose after administration and is transferred to a pool of Iron in the liver and bone marrow. The intracellular Iron becomes mostly haemoglobin in circulating red blood cells (RBCs).

Dosage

5-10 ml Iron Sucrose Injection (100-200 mg Iron) once to three times a week for adults and elderly. Limited data for children under study conditions, not recommended to exceed 0.15 ml Iron Sucrose Injection (3 mg Iron) per kg body weight once to three times per week depending on the haemoglobin level.

Administration

Intravenous injection at recommended rate
Undiluted slow intravenous injection
Infusion by drip infusion
Test dose recommended before full administration

Interaction

Not studied, should not be administered concomitantly with oral iron preparations

Contraindications

Evidence of Iron overload
Known hypersensitivity to Iron Sucrose or its inactive components
Anaemia not caused by Iron deficiency
History of allergic disorders, asthma, eczema, anaphylaxis, liver disease, and infections

Side Effects

Hypotension
Cramps/leg cramps
Nausea
Headache
Vomiting
Diarrhea
Fever
Chest pain
Hypertension
Hypervolemia
Dizziness
Dyspnea
Pneumonia
Pruritus
Hypersensitivity reactions

Pregnancy & Lactation

Pregnancy Category-B. Caution advised during nursing.

Precautions & Warnings

Periodic monitoring of hematologic and haematinic parameters required
Caution for hypersensitivity reactions and hypotension
Transferrin saturation values increase rapidly after IV administration

Use in Special Populations

Pediatric use not established
No significant differences in safety observed in elder subjects
Administration details for dialysis dependent-chronic kidney disease patients
Total cumulative doses as per specific guidelines

Overdose Effects

Excess dosage may lead to accumulation in storage sites, periodic monitoring of Ferimax parameters recommended

Therapeutic Class

Parenteral Iron Preparations

Storage Conditions

Store in a cool and dry place, protected from light, and keep out of the reach of children