Maltofer 1 gm/20 ml (IV Injection or Infusion)

20 ml vial: ৳ 1,300.00

Medicine Details

Category Details
Generic Ferric carboxymaltose
Company Incepta pharmaceuticals ltd
Also available as
Maltofer 100 mg injection Maltofer 500 mg injection Maltofer 750 mg injection

Indications

  • Treatment of iron deficiency anaemia in adult patients with intolerance to oral iron
  • Treatment of iron deficiency anaemia in adult patients with non-dialysis dependent chronic kidney disease

Description

  • Colloidal iron (III) hydroxide in complex with Carboxymaltose, a Carbohydrate polymer that releases iron

Dosage & Administration

  • Stepwise approach to determination and administration of individual iron need
  • Calculation and administration of maximum individual iron dose(s)
  • Post-iron repletion assessments

Interaction

  • No formal drug interaction studies conducted

Contraindications

  • Hypersensitivity to the active substance or any of its excipients
  • Known serious hypersensitivity to other parenteral iron products
  • Anaemia not attributed to iron deficiency
  • Evidence of iron overload or disturbances in iron utilization

Side Effects

  • Infrequent side effects which are usually mild and do not commonly result in treatment cessation
  • Common side effects include nausea, headache, dizziness, hypertension, and injection site reactions
  • Uncommon side effects include hypersensitivity, dysgeusia, tachycardia, hypotension, flushing, dyspnoea, and others
  • Rare side effects include anaphylactoid reactions, loss of consciousness, anxiety, phlebitis, syncope, and others

Pregnancy & Lactation

  • No adequate and well-controlled trials in pregnant women
  • Requires careful benefit/risk evaluation before use during pregnancy
  • Unlikely risk to breast-fed child based on limited data

Precautions & Warnings

  • Potential for serious hypersensitivity reactions, including anaphylactic-type reactions
  • Monitoring for signs and symptoms of hypersensitivity required during and after administration
  • Transient elevations in systolic blood pressure and other laboratory test alterations may occur
  • Immediate availability of personnel and therapies required for the treatment of serious hypersensitivity reactions

Use in Special Populations

  • Single maximum daily injection dose limitation for haemodialysis-dependent chronic kidney disease patients
  • Not recommended in children under 14 years

Overdose Effects

  • Excessive dosages may lead to accumulation of iron in storage sites potentially leading to hemosiderosis
  • Monitoring of iron parameters such as serum ferritin and transferrin saturation may assist in recognizing iron accumulation
  • Consider the use of an iron chelator if iron accumulation has occurred

Therapeutic Class

  • Parenteral Iron Preparations

Storage Conditions

  • Store in a cool and dry place below 30°C, away from light
  • Avoid freezing
  • Keep out of the reach of children

Related Brands