Methsolon 40 mg/ml (Injection)
40 mg vial: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Methylprednisolone acetate |
| Company | Incepta pharmaceuticals ltd |
Indications
- asthma
- atopic dermatitis
- contact dermatitis
- bullous dermatitis herpetiformis
- mycosis fungoides
- pemphigus
- severe erythema multiforme
- adrenocortical insufficiency
- hypercalcemia
- nonsuppurative thyroiditis
- ulcerative colitis
- hematologic disorders
- leukemias
- lymphomas
- sympathetic ophthalmia
- keratitis
- allergic conjunctivitis
- juvenile rheumatoid arthritis
- ankylosing spondylitis
- sarcoidosis
- aspiration pneumonitis
Pharmacology
- intracellular glucocorticoid receptors activation
- DNA promoter binding
- cell membrane crossing
- cytoplasmic receptors binding
- transcription modification
- protein synthesis
- inhibition of leukocyte infiltration
- interference with inflammatory response mediators
- suppression of humoral immune responses
- phospholipase A2 inhibitory proteins
Dosage & Administration
- intra-articular administration
- local effect
- rheumatoid arthritis
- osteoarthritis
- dermatological conditions
- systemic effect
- adrenogenital syndrome
- rheumatoid arthritis maintenance
- dermatologic lesions
- poison ivy dermatitis
- contact dermatitis
- seborrheic dermatitis
- asthma
- allergic rhinitis
- multiple sclerosis
- acute exacerbations
Interaction
- convulsions
- cyclosporine concurrent use
- hepatic enzyme induction
- metabolism inhibition
- anticoagulant effects
Contraindications
- intrathecal administration
- systemic fungal infections
- known hypersensitivity
Side Effects
- congestive heart failure
- hypertension
- sodium retention
- muscle weakness
- osteoporosis
- peptic ulcer
- abdominal distention
- increased sweating
- convulsion
- vertigo
- headache
- menstrual irregularities
- adrenocortical unresponsiveness
- pituitary unresponsiveness
- increased intraocular pressure
- glaucoma
- allergic reactions
- urticaria
- hyperpigmentation
- hypopigmentation
Pregnancy & Lactation
- Pregnancy Category C
- potential benefits vs. potential hazards
Precautions & Warnings
- ocular herpes simplex
- nonspecific ulcerative colitis
- renal insufficiency
- hypertension
- osteoporosis
- myasthenia gravis
Therapeutic Class
- Glucocorticoids
Storage Conditions
- 20-25°C