Nyclobate 0.05% (Topical Spray)
60 ml bottle: ৳ 450.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clobetasol propionate |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Psoriasis
- Dermatoses
- Lichen planus
- Discoid lupus erythematosus
- Adults
- Elderly
- Children over 1 year
Composition
- Clobetasol Propionate Cream
- Clobetasol Propionate Ointment
- Clobetasol Propionate Scalp Application
- Clobetasol Propionate Shampoo
- Clobetasol Propionate Lotion
- Clobetasol Propionate Spray
- 0.05% w/w concentration
Pharmacology
- Anti-inflammatory
- Antipruritic
- Vasoconstrictive
- Multiple mechanisms of action
- Inhibits late phase allergic reactions
- Decreases mast cell density
- Reduces cytokine production
Dosage
- Cream and Ointment usage
- Super-high potency corticosteroid
- 50 gm/week maximum dose
- 2 consecutive weeks treatment limit
- Spray application
- 50 ml weekly dose limit
- Scalp Solution application
- Shampoo application
- Limited usage for children
- Brief periods of usage
- Cutaneous route of administration
Administration
- Cutaneous administration
- Creams suitable for moist surfaces
- Ointments suitable for dry, lichenified or scaly lesions
Interaction
- CYP3A4 inhibition by co-administered drugs
Contraindications
- Rosacea
- Acne vulgaris
- Hypersensitivity
- Primary cutaneous viral infections
- Fungal and bacterial infections
- Dermatoses in children under one year of age
Side Effects
- Systemic absorption risk
- Local atrophic changes
- Pustular psoriasis
- Pigmentation changes
- Hypertrichosis
- Hypersensitivity reactions
Pregnancy & Lactation
- Limited data in pregnant women
- Abnormalities in foetal development
- Caution during lactation
Precautions & Warnings
- Avoid long-term continuous therapy
- Adrenal suppression risk in infants and children
- Atrophic changes on the face
- Appropriate anti-microbial therapy
- Careful supervision in psoriasis
- Avoid occlusive dressings
Use in Special Populations
- Avoid long-term therapy in infants and children under 12
Overdose Effects
- Unlikely acute overdosage
- Features of hypercortisolism
Therapeutic Class
- Other Topical corticosteroids
Storage Conditions
- Keep below 30°C
- Protected from light and moisture
- Do not freeze