Winpain 50 mg (Capsule)

Unit Price: ৳ 7.50 (4 x 10: ৳ 300.00)
Strip Price: ৳ 75.00

Medicine Details

Category Details
Generic Tramadol hydrochloride
Company Incepta pharmaceuticals ltd
Also available as
Winpain 100 mg injection

Indications

  • Moderate to severe painful conditions
  • Postoperative pain
  • Colic and spastic pain
  • Cancer pain
  • Joint pain
  • Neck and back pain
  • Pain associated with osteoporosis

Pharmacology

  • Centrally acting synthetic analgesic compound
  • Inhibits reuptake of neurotransmitters - serotonin and noradrenaline
  • Modifies transmission of pain impulses
  • Activates serotonergic and noradrenergic pathways
  • Stimulation of mu-opioid receptors
  • Modulation of central monoaminergic inhibitory pathways

Dosage & Administration

  • Usual doses of 50 to 100 mg every 4 to 6 hours
  • Initial dose of 100 mg for acute pain
  • Initial dose of 50 mg for chronic painful conditions
  • Sustained release: One SR capsule or tablet every 12 hours
  • Injection: 50-100 mg every 4 to 6 hours
  • Suppository: 100 mg Tramadol Hydrochloride 6 hourly for adults
  • Total daily dosage by mouth should not exceed 400 mg

Interaction

  • MAO inhibitors not recommended for combination
  • Concomitant administration of carbamazepine increases metabolism and requires adjusting dose

Contraindications

  • Hypersensitivity to the drug
  • Acute intoxication with certain substances

Side Effects

  • Dizziness/vertigo
  • Nausea
  • Constipation
  • Headache
  • Somnolence
  • Vomiting
  • Pruritus
  • CNS stimulation
  • Asthenia
  • Sweating
  • Dyspepsia
  • Dry mouth
  • Diarrhoea
  • Malaise
  • Allergic reaction
  • Weight loss
  • Vasodilatation
  • Palpitations
  • Abdominal pain
  • Anorexia
  • Flatulence
  • GI bleeding
  • Hepatitis
  • Stomatitis

Pregnancy & Lactation

  • Safe use in pregnancy not established
  • Crosses the placenta
  • Use during pregnancy justified if benefit outweighs risk to the fetus
  • Not to be administered during breastfeeding as it has been detected in breast milk

Precautions & Warnings

  • Respiratory depression risk
  • Not recommended for opioid-dependent patients
  • Caution when used with CNS depressants
  • Caution with concomitant MAO inhibitors
  • Caution in patients with increased intracranial pressure or head injury, and acute abdominal conditions

Use in Special Populations

  • Children from the age of 1 year can be given Winpain in a specific dose
  • Suppository not suitable for children and adolescents below the age of 14 years
  • SR Capsules not studied in children, safety and efficacy not established

Therapeutic Class

  • Opioid analgesics

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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