Flindof 400 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxophylline |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Bronchial asthma
- Bronchospasm
- Chronic obstructive pulmonary disease (COPD)
- Pulmonary disease with spastic bronchial component
Pharmacology
- Bronchodilator
- Inhibition of phosphodiesterase 4
- Selective bronchial smooth muscle relaxation
- Decreased affinities toward adenosine A1 and A2 receptors
- Inhibition of platelet activating factor (PAF) and leukotriene production
Dosage & Administration
- Elderly: 200 mg tablet two or three times daily
- Adults: 400 mg tablet two or three times daily
- Children >12 years: 10 ml syrup or 200 mg tablet two or three times daily
Interaction
- Not to be administered with other xanthine preparations
- Limit consumption of caffeine-containing beverages and food
- Caution with ephedrine or other sympathomimetic drugs
- Concurrent administration with certain drugs may affect hepatic clearance
Contraindications
- Known hypersensitivity to the drug or other xanthine derivatives
- Acute myocardial infarction
- Hypotension
- During lactation
Side Effects
- Nausea
- Vomiting
- Epigastric pain
- Headache
- Tachycardia
- Insomnia
- Tachypnea
- Hyperglycemia
- Albuminuria
- Severe cardiac arrhythmias
- Tonic-clonic seizure
Pregnancy & Lactation
- Animal tests do not interfere with pre and postnatal growth
- Careful evaluation for use during pregnancy
- Contraindicated during lactation
- No documented effect on patient's alertness
Precautions & Warnings
- Factors affecting hepatic clearance
- Monitoring blood levels in certain cases
- Caution in patients with cardiac disease, hypertension, hypoxemia, etc.
- No risk of addiction or dependence
Overdose Effects
- Severe cardiac arrhythmias
- Tonic-clonic seizure
- No specific antidote
- Symptomatic treatment of cardiovascular collapse
Therapeutic Class
- Bronchodilator
- Methyl xanthine derivatives
Storage Conditions
- Dry place away from light and heat
- Keep out of reach of children
- Use only on prescription of specialist physician