Maxrin 0.4 mg (Capsule (Modified Release))
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
Category | Details |
---|---|
Generic | Tamsulosin hydrochloride |
Company | Square pharmaceuticals plc |
Indications
- Treatment of functional symptoms of Benign Prostatic Hyperplasia (BPH)
Pharmacology
- Tamsulosin is a selective alpha1 adrenoceptor blocking agent
- Improves urine flow rate
- Reduces symptoms of BPH
- Absorption is 90% complete following oral administration under fasting conditions
- Metabolized by cytochrome P450 enzymes in the liver
Dosage & Administration
- Daily dosage of Tamsulosin Hydrochloride 0.4 mg
- May be increased to Tamsulosin Hydrochloride 0.8 mg if necessary
- To be taken after meal at night
- Capsule should be swallowed whole with a glass of water
Interaction
- Concurrent administration of other alfa1-adrenoceptor antagonists could lead to hypotensive effects
- No interactions observed with atenolol, enalapril, or nifedipine
- Cimetidine may increase plasma levels while frusemide may decrease levels
- No interactions at the level of hepatic metabolism observed with certain drugs
Contraindications
- Hypersensitivity to Tamsulosin hydrochloride
- History of orthostatic hypotension
- Severe hepatic insufficiency
Side Effects
- Dizziness
- Abnormal ejaculation
- Headache
- Asthenia
- Postural hypotension
- Palpitations
Pregnancy & Lactation
- Not recommended for use during pregnancy and lactation
Precautions & Warnings
- Transient postural symptoms may occur after the first dose
- Use in patients with micturition syncope is not advised
- Effects on ability to drive and use machines are unknown
Overdose Effects
- Acute hypotension likely to occur after overdosage
- Cardiovascular support should be given
- Renal function should be monitored
- General supportive measures should be applied
Therapeutic Class
- BPH/ Urinary retention/ Urinary incontinence
Storage Conditions
- Store in a cool and dry place below 30°C, protected from light
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