Methigic 2 mg (Tablet)

Unit Price: ৳ 3.00 (5 x 10: ৳ 150.00)

Strip Price: ৳ 30.00

Medicine Details

Category	Details
Generic	Methylprednisolone
Company	Square pharmaceuticals plc
Also available as	Methigic 4 mg tablet Methigic 8 mg tablet Methigic 16 mg tablet

Potent anti-inflammatory steroid with greater anti-inflammatory potency than Prednisolone and less tendency to induce sodium and water retention.

Pharmacodynamic Properties: Potent anti-inflammatory agent with the capacity to profoundly inhibit the immune system
Pharmacokinetic Properties: High absolute bioavailability, rapid absorption, widely distributed into tissues, metabolized in the liver

Usual range of 2-48 mg daily in divided doses
Initial dosage varies from 4-48 mg per day depending on the specific disease entity being treated
Maintenance dosage determined by decreasing the initial drug dosage in small decrements at appropriate time intervals

Inhibition of metabolism by Erythromycin, Clarithromycin, Phenobarbital, Phenytoin, Rifampin, and Ketoconazole
Increased effect by estrogens, including birth control pills
Reduced metabolism with Cyclosporin and Methigic
Potential increase or decrease in the effect of blood thinners

Systemic fungal infections and known hypersensitivity to components

Range from fluid retention to serious irreversible bodily damage, including potential corticosteroid insufficiency symptoms upon discontinuation

Pregnancy category C; use in nursing mothers not adequately evaluated

Adrenocortical insufficiency may persist for months after discontinuation of therapy
Enhanced effect on patients with hypothyroidism and in those with cirrhosis
Cautious use in patients with ocular herpes simplex and hypoprothrombinemia
Careful observation of growth and development of infants and children on prolonged therapy

Rare occurrences with no specific antidote available; treatment is supportive and symptomatic