Mirapro 15 mg (Tablet)

Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Mirtazapine
Company Square pharmaceuticals plc
Also available as
Mirapro 75 mg tablet

Title

  • Mirapro Tablets

Categories

  • Medicine
  • Antidepressant
  • Pharmaceutical

Description

  • Indicated for the treatment of major depressive disorder (MDD)
  • Enhances central noradrenergic and serotonergic activity
  • Rapidly and well-absorbed after oral administration
  • Recommended starting dose of 15 mg/day for adults
  • Has clinically significant drug-drug interactions with MAOI and other serotonergic drugs
  • Contraindicated in patients with known hypersensitivity to Mirtazapine or excipients
  • Common side effects include dizziness, drowsiness, dry mouth, and increased appetite
  • Pregnancy Category-C
  • Should be stored below 30°C and away from light and moisture

Dimensions

  • Tablet form

Color Options

  • N/A

Functions

  • Treats major depressive disorder
  • Enhances central noradrenergic and serotonergic activity
  • Antagonist at central presynaptic α2-adrenergic inhibitory autoreceptors and heteroreceptors
  • Potent antagonist of 5-HT2 and 5-HT3 receptors
  • Antagonist of histamine (H1) receptors

Materials

  • Active constituent: Mirtazapine

Technical Specifications

  • Binding of mirtazapine to plasma proteins is approximately 85%
  • Mean half-life of elimination is 20-40 hours
  • Linear pharmacokinetics within the recommended dose range
  • Metabolized and eliminated via urine and faeces

Design Elements

  • N/A

Usability Features

  • Recommended starting dose of 15 mg/day
  • Once-a-day dosing
  • Dose should be made at intervals of less than 1 to 2 weeks
  • Not recommended for use in children
  • Should be taken as a single dose, preferably in the evening or prior to sleep
  • Has elimination half-life of approximately 20-40 hours
  • Should not be used within 14 days of initiating or discontinuing therapy with MAOI
  • Should be stored away from light and moisture

Dosage & Administration

  • Recommended starting dose for adults is 15 mg/day
  • Effective dose range is generally 15 to 45 mg/day
  • Missed doses should be taken as soon as remembered, unless close to the next scheduled dose
  • Dose changes should be made at intervals of less than 1 to 2 weeks
  • Not recommended for use in children

Interactions

  • Clinically significant drug-drug interactions with MAOI
  • May interrupt the metabolism or activity of Carbamazepine, Phenytoin, or Cimetidine
  • Patient should avoid Alcohol & Diazepam

Contraindications

  • Contraindicated in patients with known hypersensitivity to Mirtazapine or excipients
  • Concomitant use with MAO inhibitor is contraindicated
  • Should not be used within 14 days of initiating or discontinuing therapy with MAOI

Side Effects

  • Common side effects include dizziness, drowsiness, dry mouth, and increased appetite

Pregnancy & Lactation

  • Pregnancy Category-C
  • Patients should notify physician if they become pregnant or intend to become pregnant during therapy
  • Patients should notify physician if they are breastfeeding an infant

Precautions & Warnings

  • Patients, caregivers, and families should be alert to the emergence of certain behavior changes
  • Warned about the risk of developing agranulocytosis
  • May impair judgment, thinking, and motor skills
  • Clinically significant ALT (SGPT) elevations may occur

Therapeutic Class

  • Atypical anti-depressant drugs

Storage Conditions

  • Should be stored below 30°C and away from light and moisture

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