Ceftoril 90 mg/5 ml (Powder for Suspension)

60 ml bottle: ৳ 480.00

Medicine Details

Indications

  • Treatment of Acute Bacterial Exacerbations of Chronic Bronchitis
  • Treatment of Acute Bacterial Otitis Media
  • Treatment of Pharyngitis and Tonsillitis

Pharmacology

Ceftibuten is a semi-synthetic Cephalosporin antibiotic for oral administration.

Dosage & Administration

  • Adult Dosage: 400 mg orally every 24 hours for various conditions like Otitis Media, Tonsillitis, Bronchitis, Cystitis, Pneumonia, Sinusitis, Urinary Tract Infection
  • Pediatric Dosage: Varies depending on the condition

Interaction

  • Theophylline & Antacid do not alter the pharmacokinetic profile of Ceftoril
  • Ranitidine increases the Cmax & AUC of Ceftoril

Contraindications

Ceftibuten is contraindicated in patients with known allergy to the cephalosporin group of antibiotics.

Side Effects

  • Nausea
  • Headache
  • Diarrhea
  • Dyspepsia
  • Dizziness
  • Abdominal Pain
  • Vomiting

Pregnancy & Lactation

  • Pregnancy Category B
  • Use in pregnancy only when the benefit clearly outweighs the risk
  • Caution should be exercised when administered to nursing women

Precautions & Warnings

  • Prolonged treatment may result in the possible emergence and overgrowth of resistant organisms
  • Careful observation of the patient is essential
  • The dose of Ceftoril may require adjustment in patients with varying degrees of renal insufficiency
  • Ceftoril should be prescribed with caution to individuals with a history of gastrointestinal disease, particularly colitis

Use in Special Populations

  • Renal Impairment: Dose adjustments based on Creatinine Clearance (CrCl)
  • Hepatic Impairment: Dose adjustment is not necessary

Therapeutic Class

Third generation Cephalosporins

Reconstitution

  • Process of reconstituting the suspension with purified water and granules
  • Use of measuring cup or dropper for reconstituted suspension
  • Prepared suspension to be consumed within 14 days if kept in a refrigerator
  • Shake the bottle well each time before use

Storage Conditions

Store below 25°C, protected from light and moisture. Suspension can be used for 14 days after reconstitution if kept at 2°C to 8°C.

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