Albezen 400 mg (Chewable Tablet)
Unit Price: ৳ 3.00 (25 x 2: ৳ 150.00)
Strip Price: ৳ 6.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Albendazole |
| Company | Zenith pharmaceuticals ltd |
Indications
- Single infestations of hookworm (Ancylostoma)
- Mixed infestations of hookworm (Ancylostoma), roundworm (Ascaris), threadworm (Enterobius), whipworm (Trichuris), strongyloides, tapeworm, opisthorchi, hydatid
Description
- Active against most nematodes and some cestodes
- Used in the treatment of intestinal nematode infections
- Used in higher doses in the treatment of hydatid disease
- Vermicidal, ovicidal, and larvicidal activity
- Inhibitory effect on tubulin polymerization
Pharmacology
- Broad spectrum anthelmintic
- Exhibits vermicidal, ovicidal, and larvicidal activities
- Blocks glucose uptake in susceptible helminths
- Depletes energy level of helminths
- Binds and inhibits parasite tubulin polymerization
- Extensively metabolized, probably in the liver
- Poorly absorbed from the gastrointestinal tract
Dosage & Administration
- Adult dosage: 400 mg as a single dose for various infestations
- Children dosage: 200 mg for 1-2 years, not recommended for under 1 year
- Hydatid disease treatment: 400 mg twice daily for patients over 60 kg
- Hydatid disease treatment: 15 mg/kg body weight daily for patients under 60 kg
- Additional dosages for cystic and alveolar echinococcosis, and giardiasis
Interaction
- No reported pharmacodynamic or pharmacokinetic interactions
Contraindications
- Not normally used in neonates
- Reduced dosage for children under 10 kg
- Not recommended during pregnancy or for women thought to be pregnant
- No evidence to alter dosage in renal, hepatic, or cardiac failure
Side Effects
- Gastrointestinal disturbances
- Headache, dizziness
- Changes in liver enzymes
- Rarely reversible alopecia
- Rash, fever
- Blood disorders including leucopenia and pancytopenia
- Allergic shock if cyst leakage
- Convulsion and meningism in cerebral disease
Pregnancy & Lactation
- US FDA Pregnancy category: C
- Avoided in pregnancy and lactation unless the potential benefits outweigh the possible risks to the fetus
Precautions & Warnings
- Blood counts and liver function tests before treatment and during each cycle
- Precautions for breastfeeding
- Exclusion of pregnancy before treatment
- Constant medical supervision for treatment of Echinococcosis
Therapeutic Class
- Anthelmintic
Storage Conditions
- Keep in a dry place
- Away from light and heat
- Keep out of the reach of children