Uroflo Plus 0.4 mg+0.5 mg (Capsule)
Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tamsulosin hydrochloride dutasteride |
| Company | Beximco pharmaceuticals ltd |
Indications
- Treatment of moderate to severe symptoms of benign prostatic hyperplasia (BPH)
- Reduction in the risk of acute urinary retention and surgery in patients with moderate to severe symptoms of BPH
Pharmacology
- Tamsulosin affects dynamic component of BPH by inhibiting alpha<sub>1</sub>-adrenoreceptors
- Dutasteride affects static component of BPH by inhibiting conversion of Testosterone to Dihydrotestosterone (DHT)
Dosage & Administration
- Recommended dose: Tamsulosin Hydrochloride 0.4 mg & Dutasteride 0.5 mg
- Swallow capsules whole, not chewed or opened
Interaction
- No formal drug interaction studies with potent CYP3A4 inhibitors
- Long-term combination with potent CYP3A4 inhibitors may increase serum concentrations of Dutasteride
Contraindications
- Contra-indicated in women, children, patients with hypersensitivity to Dutasteride or Tamsulosin, soya, peanut or any excipients
Side Effects
- Impotence
- Decreased libido
- Breast disorders (including breast enlargement and tenderness)
- Ejaculation disorders
- Dizziness
Pregnancy & Lactation
- Contra-indicated for use by women
- Dutasteride may affect semen characteristics in healthy men
- Effects on sperm counts or function of Tamsulosin not evaluated
Precautions & Warnings
- Prescribed after careful benefit risk assessment
- Caution for patients with renal impairment, hypotension, hepatic impairment, and history of orthostatic hypotension
Overdose Effects
- No data available for overdose of Tamsulosin-Dutasteride combination
- In case of acute hypotension after Tamsulosin overdose, cardiovascular support should be given