Avlomox 500 mg/vial (IM/IV Injection)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amoxicillin trihydrate |
| Company | Aci limited |
| Also available as |
Indications
- Ear, nose and throat infections
- Lower respiratory tract infections
- Skin and soft tissue infections
- Genito-urinary tract infections
- Venereal disease
- Dental abscess
Pharmacology
Amoxicillin is a broad spectrum penicillin effective against a wide range of Gram-positive and Gram-negative bacteria. It acts through the inhibition of cell wall biosynthesis.
Dosage
- Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections
- Children: 125 mg three times daily, increasing up to 250 mg three times daily for severe infections
- Severe or recurrent purulent respiratory infection: 3 gm every 12 hours
- Otitis media: Recommended dose is 1 g three times daily for adult and 40 mg/kg body weight daily in 3 divided doses for children
- Pneumonia: Recommended dose is 500-1000 mg three times daily
- Dental abscess: Recommended dose is 3 gm, repeated after 10-12 hours
- Urinary tract infections: Recommended dose is 3 gm, repeated after 10-12 hours
- Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm
- In renal impairment: It may be necessary to reduce the total daily dosage
Administration
Reconstituted suspension can be administered by adding the required amount of suspension to milk, fruit juice, water. These preparations should then be taken immediately.
Interaction
Concurrent use of Avlomox and Probenecid may result in increased and prolonged blood levels of Avlomox.
Contraindications
Amoxicillin is contraindicated in penicillin hypersensitive patients
Side Effects
- Diarrhoea
- Indigestion
- Rash
- Pseudo-membranous colitis
Pregnancy & Lactation
Amoxicillin is category B. Caution should be exercised when administered to a lactating mother.
Precautions & Warnings
The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur, Avlomox should be discontinued and appropriate therapy should be instituted.
Therapeutic Class
Broad spectrum penicillins
Reconstitution
- Intramuscular: Add 2.5 ml water for injection to Amoxicillin 500 mg injection vial
- Intravenous: Dissolve Amoixcillin 500 mg injection in 10 ml water for injection
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.