Doximar 200 mg (Tablet)
Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxophylline |
| Company | Aci limited |
| Also available as |
Title, Categories & Description
- Doximar Tablet
- Medicine
- Bronchodilator for Bronchial Asthma, Bronchospasm, COPD, and Pulmonary Diseases with Spastic Bronchial Component
- Methylxanthine Derivatives
- Used on prescription of specialist physician
Dosage & Administration
- 200mg and 400mg tablet
- 10ml syrup
- Dosage varies for elderly, adults, and children based on age and physician's prescription
- Extended-release (SR) tablet available for daily dose of 400 mg
Indications
- Treatment of Bronchial asthma
- Bronchospasm
- COPD
- Pulmonary disease with spastic bronchial component
Pharmacology
- Doxophylline - novel bronchodilator with a dioxolane group in position 7
- Selective inhibitor of phosphodiesterase 4
- Relaxes bronchial smooth muscle
- Decreased affinities toward adenosine A1 and A2 receptors
- Inhibits platelet activating factor (PAF) and leukotriene production
Interaction
- Not to be administered with other xanthine preparations
- Limit consumption of caffeine-containing beverages and food
- Exercise caution when administered with sympathomimetic drugs and specific medications such as erythromycin, TAO, lincomycin, clindamycin, allopurinol, cimetidine, influenza vaccine, propanolol, phenytoin, and other anticonvulsants
- Dosage adjustment may be necessary in certain cases
Side Effects & Overdose
- Possible side effects include nausea, vomiting, epigastric pain, headaches, insomnia, tachycardia, and more
- Overdose may lead to severe cardiac arrhythmias and tonic-clonic seizures
- No specific antidote available for overdose
Contraindications
- Hypersensitivity to the drug or other xanthine derivatives
- Acute myocardial infarction
- Hypotension
- During lactation
Pregnancy & Lactation
- Use during pregnancy to be carefully evaluated based on risk-benefit ratio
- Contraindicated during lactation
- No interference with pre and postnatal growth in animal tests
Precautions & Warnings
- Factors affecting hepatic clearance may influence drug plasma levels
- Caution in patients with cardiac disease, hypertension, elderly, severe hypoxemia, hyperthyroidism, chronic corpulmonale, congestive heart failure, liver disease, peptic ulcer, and renal impairment
- Special caution in congestive heart failure patients due to slower drug clearance
- No risk of addiction or dependence
Overdose Effects
- Severe cardiac arrhythmias and tonic-clonic seizures may occur
- Discontinuation of treatment may be necessary if signs of toxicity appear
- Symptomatic treatment of cardiovascular collapse in case of overdose
Therapeutic Class
- Bronchodilator
- Methyl xanthine derivatives
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
- Use only on prescription of specialist physician