Floxabid 200 mg/100 ml (IV Infusion)

100 ml bottle: ৳ 146.44

Medicine Details

Indications

  • Treatment of single infection or mixed infections
  • Treatment of infections resistant to other antibiotics
  • Treatment of urinary, respiratory, and gastrointestinal tract infections
  • Treatment of skin and soft tissue infections
  • Treatment of gonorrhea
  • Treatment of pelvic infections
  • Treatment of eye, ear, nose and throat infections
  • Treatment of bone and joint infections
  • Treatment of biliary, intra-abdominal, and gastrointestinal infections

Pharmacology

  • Synthetic quinolone anti-infective agent
  • Broad spectrum activity
  • Activity against gram negative and positive aerobic bacteria
  • Bactericidal action
  • Interference with DNA gyrase enzyme
  • Rapid and well absorption from G.I. tract
  • Widely distributed in body tissues and fluids
  • About 3.5 hours half-life
  • Excretion in urine

Dosage

  • Dosage determined by severity, type, and sensitivity of infection
  • Dosage range for adults: 100-750 mg twice daily
  • Specific dosages for different types of infections
  • Dosage adjustments for impaired renal function
  • No dosage adjustment for the elderly
  • Use not recommended for children with arthropathy risk
  • Duration of treatment based on severity and clinical response
  • Specific dosages for extended-release tablets and IV infusion

Administration

  • Instructions for use of IV infusion
  • Checking for leaks and cloudy solution
  • Instructions for setting up and regulating rate of administration

Interaction

  • Avoid concurrent administration with specific antacids and products containing calcium, iron, or zinc
  • Caution against concurrent use with milk or dairy products

Contraindications

  • Hypersensitivity to Ciprofloxacin or other quinolones

Side Effects

  • Gastrointestinal disturbances
  • Central nervous system disturbances
  • Hypersensitivity reactions
  • Joint pain
  • Photosensitivity
  • Increase in liver enzymes
  • Risk of hypoglycemia and mental health adverse effects

Pregnancy & Lactation

  • No evidence of teratogenicity, impairment of fertility or peri/post natal development in reproduction studies
  • Arthropathy risk in immature animals
  • Avoid use during pregnancy and nursing

Precautions & Warnings

  • Caution in patients with CNS disorders
  • Caution against specific concurrent administrations
  • Caution against concurrent use with milk or yogurt

Use in Special Populations

  • Not a drug of first choice in pediatric population

Overdose Effects

  • Seizures, hallucinations, confusion
  • Abdominal discomfort
  • Renal and hepatic impairment
  • Crystalluria, haematuria, reversible renal toxicity

Therapeutic Class

  • 4-Quinolone preparations
  • Anti-diarrhoeal antimicrobial drugs

Storage Conditions

  • Keep below 30°C temperature
  • Protected from light and moisture
  • Keep out of the reach of children

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