Mobifen 12.5 mg (Suppository)
Unit Price: ৳ 9.00 (4 x 5: ৳ 180.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Aci limited |
| Also available as |
Indications
- Rheumatology
- Inflammatory and degenerative forms of rheumatism
- Chronic involutive
- Polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Spondylarthroses
- Acute gout
- Peri-articular rheumatic disorders
- Surgery and Traumatology
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Obstetrics and Gynecology
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Otorhinolaryngology
- Pre-operative medication for prevention of pain, inflammation, and swelling
- Dentistry
- Post-operative and post-traumatic pain, inflammation, and swelling
- Urogenital tract
- Renal and biliary colic
Pharmacology
- Potent non-steroidal anti-inflammatory drug (NSAID)
- Anti-rheumatic properties
- Analgesic properties
- Antipyretic properties
- Uricosuric effect
- Inhibition of prostaglandin biosynthesis
- Rapid and complete absorption from the gastro-intestinal tract
- Metabolized in the liver
- First pass metabolism
Dosage & Administration
- Diclofenac FC Tablet for adults: 75-150 mg daily in 2 to 3 divided doses
- Diclofenac SR Tablet for adults: 1 tablet daily, taken whole with liquid, preferably at meal times. Daily dose can be increased to 150 mg
- Diclofenac SR Tablet for children: 1-3 mg of diclofenac/kg body wt. daily in divided doses
- Diclofenac Dispersible Tablet for adults: 2-3 tablets daily, maximum daily dose is 150 mg. In milder cases, 2 tablets of Diclofenac DT per day are sufficient
- Diclofenac Dispersible Tablet for children: 1-3 mg/kg body weight
- Diclofenac TR Capsule: One capsule daily, preferably after mealtimes
- Diclofenac Suppository for adults: 50 mg suppository 2-3 times daily, maximum daily dose is 150 mg
- Diclofenac injection for adults: 1 ampoule daily, may be increased up to 2 ampoules daily in serious cases
- Diclofenac Gel: 2-4 g of Diclofenac gel applied 3-4 times daily to the affected area
Interaction
- Increased plasma concentrations of lithium and digoxin
- Reports of increased risk of haemorrhage with combined use of diclofenac and anticoagulant therapy
- Diclofenac can be given together with oral antidiabetic agents without influencing their clinical effect
- Cases of nephrotoxicity reported in patients receiving cyclosporin and diclofenac concomitantly
- Serious toxicity reported when methotrexate and NSAIDs are given within 24 hours of each other
- Convulsions may occur due to an interaction between quinolones and NSAIDs
- Co-administration of diclofenac with other systemic NSAIDs and steroids may increase the frequency of unwanted effects
- Plasma levels of each is lowered with co-administration of diclofenac with aspirin
Contraindications
- Hypersensitivity to any ingredient of the products
- Peptic ulcer
- Asthmatic patients in whom attack with asthma, urticaria or acute rhinitis are precipitated by acetylsalicylic acid or by other drugs with prostaglandin synthetase inhibitor
- Not to be used under occlusive airtight dressings
Side Effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions such as rash and eczema
- Local irritation and reddening of the skin
- Skin rash
Pregnancy & Lactation
- Employed only for compelling reasons during pregnancy
- Lowest effective dose should be used
- Not recommended during the first trimester of pregnancy
- Not recommended during pregnancy
- Insignificant quantity detected in breast milk
Precautions & Warnings
- Close observation for peptic ulceration or gastrointestinal bleeding
- Keep out of contact with the eyes or mucus membranes
- Not to be taken by mouth
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store in a cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children