Seroxyn (25 mcg+125 mcg)/puff (Inhaler)

120 metered doses: ৳ 596.79

Medicine Details

Indications

  • Regular treatment of asthma
  • Combination product
  • Long-acting β2-agonist
  • Inhaled corticosteroid
  • Asthma patients not adequately controlled
  • Asthma patients already adequately controlled

Pharmacology

  • Salmeterol Xinafoate
  • Selective beta-2 agonist
  • Treatment of asthma
  • Diffuse airway obstruction
  • Fluticasone Propionate
  • Corticosteroid
  • Glucocorticoid activity

Dosage

  • Inhaler for adults and adolescents
  • Inhaler for children (4-12 years)
  • Inhalation capsule for adult and adolescent
  • Starting dosages based on asthma severity
  • Maximum recommended dosage
  • Maxhaler for adults and adolescents
  • Maxhaler for children
  • Maxhaler for COPD

Administration

  • Correct usage of inhaler
  • Steps for effective inhaler use
  • Instructions for cleaning inhaler

Interaction

  • Avoidance of non-selective β-blockers
  • Avoidance of selective β-blockers
  • Avoidance of strong CYP3A4 inhibitors

Contraindications

  • Hypersensitivity to salmeterol xinafoate
  • Hypersensitivity to fluticasone propionate
  • Not for primary treatment of status asthmaticus

Side Effects

  • Tremor
  • Headache
  • Cardiac arrhythmia
  • Hypersensitivity reactions
  • Oropharyngeal irritation
  • Hoarseness
  • Candidiasis
  • Cutaneous hypersensitivity reactions
  • Muscle cramps

Pregnancy & Lactation

  • Use during pregnancy only if benefit outweighs risk
  • Insufficient experience in human pregnancy
  • Use in lactating mothers only if benefit outweighs risk
  • Very low concentrations in human breast milk

Precautions & Warnings

  • Avoid initiation during exacerbation
  • Not for relief of acute symptoms
  • Vigilance for possible development of pneumonia
  • Review of patient for systemic effects

Use in Special Populations

  • Reduction in growth velocity in paediatric patients

Overdose Effects

  • Signs and symptoms of overdose for Salmeterol
  • Seizures
  • Angina
  • Hypertension or hypotension
  • Tachycardia
  • Signs and symptoms of overdose for Fluticasone Propionate
  • Temporary suppression of adrenal function

Therapeutic Class

  • Long-acting selective β-adrenoceptor stimulants
  • Respiratory corticosteroids

Storage Conditions

  • Pressurised canister
  • Avoid puncturing, breaking or incinerating
  • Avoid storage in direct sunlight or heat
  • Store below 30°C
  • Keep away from eyes
  • Keep away from children

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