Doxoven 200 mg (Tablet)
Unit Price: ৳ 8.00 (10 x 10: ৳ 800.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxophylline |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Title and Categories
- Doxoven
- Bronchodilator
- Methyl xanthine derivatives
Indications
- Bronchial asthma
- Bronchospasm
- Chronic obstructive pulmonary disease (COPD)
- Pulmonary disease with spastic bronchial component
Pharmacology
- Novel bronchodilator
- Selective inhibition of phosphodiesterase 4
- Relaxes bronchial smooth muscle
- Decreased affinities towards adenosine A1 and A2 receptors
- Inhibition of platelet activating factor (PAF)
- Inhibition of leukotriene production
Dosage and Administration
- Elderly dosage: 200 mg tablet two or three times daily
- Adults dosage: 400 mg tablet two or three times daily
- Children dosage: >12 years - 10 ml syrup or 200 mg tablet two or three times daily, 6-12 years - 6-9 mg/kg body weight two times daily
- Doxophylline SR tablet for 400 mg daily dose
Interaction
- Avoid admin with other xanthine preparations
- Limit caffeine-containing beverages and food
- Caution with ephedrine or other sympathomimetic drugs
- Concurrent administration may affect hepatic clearance
- Increase in dosage with concurrent phenytoin, anticonvulsants, or cigarette smoking
Contraindications
- Known hypersensitivity to the drug or other xanthine derivatives
- Acute myocardial infarction
- Hypotension
- Lactation
Side Effects
- Nausea
- Vomiting
- Epigastric pain
- Headache
- Irritability
- Insomnia
- Tachycardia
- Extrasystoles
- Tachypnea
- Hyperglycemia
- Albuminuria
- Severe cardiac arrhythmias
- Tonic-clonic seizure
Pregnancy & Lactation
- Use during pregnancy should be evaluated based on risk-benefit ratio
- Contraindicated during lactation
- No interference with pre and postnatal growth in animal tests
Precautions & Warnings
- Age, congestive heart failure, chronic obstructive pulmonary disease, hepatic diseases may reduce clearance
- Caution in patients with cardiac disease, hypertension, hypoxemia, hyperthyroidism, liver disease, renal impairment
- Slow clearance in congestive heart failure patients
- No risk of addiction or dependence
Overdose Effects
- Severe cardiac arrhythmias
- Tonic-clonic seizures
- Discontinue treatment and resume at lower doses after subsiding of symptoms
Therapeutic Class
- Bronchodilator
- Methyl xanthine derivatives
Storage Conditions
- Keep in dry place away from light and heat
- Keep out of reach of children
- Use only on prescription of specialist physician