Doxoven 100 mg/5 ml (Syrup)
100 ml bottle: ৳ 110.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxophylline |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Title
- Doxoven
Categories
- Bronchodilator
- Methyl xanthine derivatives
Description
- Doxoven is a medicine used to treat bronchial asthma, bronchospasm, chronic obstructive pulmonary disease (COPD), and pulmonary disease with spastic bronchial component. It contains doxophylline, a bronchodilator that selectively inhibits phosphodiesterase 4, relaxes bronchial smooth muscle, and has a better safety profile compared to Theophylline. The recommended dosage for adults is 400 mg tablet two or three times daily, and for children is based on their age and body weight. Doxoven should not be administered with other xanthine preparations, and caution should be exercised with certain drugs. It is contraindicated in individuals with known hypersensitivity to the drug or other xanthine derivatives, as well as in patients with acute myocardial infarction, hypotension, and during lactation. Adverse effects may include nausea, vomiting, headache, tachycardia, and in rare cases, hyperglycemia or albuminuria.
Dimensions
- N/A
Color options
- N/A
Functions
- Treats bronchial asthma
- Relaxes bronchial smooth muscle
- Inhibits phosphodiesterase 4
- Bronchodilator
Materials
- N/A
Technical specifications
- Doxophylline content: 400 mg tablet
- Recommended Dosage for Adults: 400 mg tablet two or three times daily
- Recommended Dosage for Children: Syrup or tablet based on age and body weight
- Methyl xanthine derivatives
Design elements
- N/A
Usability features
- Pregnancy and Lactation: Use of the drug during pregnancy requires careful evaluation
- Storage: Keep in a dry place away from light and heat
Indications
- Bronchial asthma
- Bronchospasm
- Chronic obstructive pulmonary disease (COPD)
- Pulmonary disease with spastic bronchial component
Mode of action
- Doxophylline selectively inhibits phosphodiesterase 4
- Structurally differs from Theophylline due to the presence of a dioxolane group in position 7
- Has decreased affinities toward adenosine A1 and A2 receptors
- Inhibits platelet activating factor (PAF) and generation of leukotriene production
Dosage and administration
- Elderly: 200 mg tablet two or three times daily
- Adults: 400 mg tablet two or three times daily
- Children age >12 years: 10 ml syrup or 200 mg tablet two or three times daily
- Children age 6-12 years: 6-9 mg/kg body weight two times daily
- Doxophylline SR tablet to be taken once daily if required daily dose is 400 mg
Interaction
- Not to be administered with other xanthine preparations
- Limit consumption of beverages and food containing caffeine
- Caution with ephedrine or other sympathomimetic drugs
- Concurrent administration of certain drugs may reduce hepatic clearance
- Some drugs may increase the clearance of xanthine derivatives
Contraindications
- Known hypersensitivity to the drug or other xanthine derivatives
- Acute myocardial infarction
- Hypotension
- During lactation
Side effects
- Nausea
- Vomiting
- Headache
- Tachycardia
- Hyperglycemia
- Albuminuria
- Severe cardiac arrhythmias
- Tonic-clonic seizure
Pregnancy and lactation
- Animal tests show no interference with pre and postnatal growth
- Use during pregnancy requires careful evaluation
- Contraindicated during lactation
- Does not affect the ability to drive and use machines
Precautions and warnings
- Factors may reduce hepatic clearance of xanthine derivatives
- Caution in patients with cardiac disease, hypertension, elderly, severe hypoxemia, hyperthyroidism, liver disease, peptic ulcer, renal impairment
- No risk of addiction or dependence
Overdose effects
- Severe cardiac arrhythmias
- Tonic-clonic seizure
- Discontinuation of treatment may be required
- No specific antidote available
Therapeutic class
- Bronchodilator
- Methyl xanthine derivatives
Storage conditions
- Dry place away from light and heat
- Keep out of the reach of children
- Use only on prescription of specialist physician