Xovir 400 mg (Tablet)
Unit Price: ৳ 22.00 (3 x 8: ৳ 528.00)
Strip Price: ৳ 176.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Acyclovir oral |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Indications
- Treatment of viral infections due to Herpes simplex virus (type I & II) and Varicella zoster virus
- Treatment of Herpes simplex virus infections of the skin and mucous membranes
- Prophylaxis of Herpes simplex infections in immunocompromised patients
Pharmacology
- Synthetic purine derivative
- Interference with DNA synthesis
- Inhibition of viral replication
- Conversion to Aciclovir Triphosphate
- Absorption in gastrointestinal tract
- Widely distributed into body tissues and fluids
- Excretion through kidney
Dosage & Administration
- Treatment of initial herpes simplex: 200 mg 5 times daily usually for 5 days
- Prevention of recurrence of herpes simplex: 200 mg 4 times daily or 400 mg twice daily
- Prophylactic treatment of herpes simplex in immunocompromised patients: 200 to 400 mg 4 times daily
- Treatment of vericella (chicken pox): dosage varies based on age and weight
- Treatment of herpes zoster (Shingles): 800 mg 5 times daily for 7 days
- Renal Impairment: Dose reduction recommended
Interaction
- Probenecid reduces Aciclovir excretion and increases plasma concentration
Contraindications
- Hypersensitivity to Aciclovir
Side Effects
- Rash
- Gastrointestinal disturbance
- Rise in bilirubin and liver-related enzymes
- Increase in blood urea and creatinine
- Decrease in hematological indices
- Headache
- Neurological reaction
- Fatigue
Pregnancy & Lactation
- Pregnancy category B
- Use during pregnancy requires balancing potential benefit and risk to the fetus
- Caution in nursing mothers
Precautions & Warnings
- Caution in patients with renal impairment
- Dose adjustment according to creatinine clearance
- Monitor neutrophil count in neonates
Therapeutic Class
- Herpes simplex & Varicella-zoster virus infections
Storage Conditions
- Store below 25°C
- Protect from light and moisture
- Keep out of the reach of children