Afix 400 mg (Tablet)
Unit Price: ৳ 50.00 (1 x 7: ৳ 350.00)
Strip Price: ৳ 350.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefixime trihydrate |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Treatment of Upper Respiratory Tract Infections (URTI)
- Treatment of Lower Respiratory Tract Infections
- Treatment of Urinary Tract Infections (UTI)
- Clinical efficacy against Streptococcus pneumonia
- Clinical efficacy against Escherichia coli
- Clinical efficacy against Proteus mirabilis
- High stability in the presence of beta-lactamase enzymes
Pharmacology
- Third generation semisynthetic cephalosporin antibiotic
- Oral administration
- Bactericidal against a broad spectrum of bacteria
- Interferes with bacterial cell wall synthesis
- High stability in the presence of Beta-lactamase enzyme
- Approximately 40-50% absorption whether administered with or without food
Dosage & Administration
- Usual course of treatment is 7 days
- Recommended adult dosage: 200-400 mg daily
- Recommended dosage for children: 8 mg/kg/day
- Different dosages for different age groups
- Recommended dosage for typhoid treatment
Interaction
- Potential increases in prothrombin times
- Careful administration in patients receiving anticoagulant therapy
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Mild and self-limiting adverse reactions
- Frequent gastrointestinal disturbances
- Central nervous system effects: headache and dizziness
- Hypersensitivity reactions: rash, pruritis, urticaria
- Hematological and clinical chemistry effects: thrombocytopenia, leukopenia
- Mild transient change in liver and renal function tests
- Miscellaneous: genital pruritis and vaginitis
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Use during pregnancy only if clearly needed
- Caution advised in nursing women
Precautions & Warnings
- Caution in patients with hypersensitivity to other drugs
- Caution in penicillin-sensitive patients
- Administration with caution in patients with markedly impaired renal function
- Potential alteration of normal flora of the colon
Overdose Effects
- Gastric Lavage may be indicated
- No specific antidote exists
- Not significantly removed from circulation by dialysis
Therapeutic Class
- Third generation Cephalosporins
Storage Conditions
- Store below 30°C temperature
- Protected from light and moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C16H15N5O7S2
Common Questions about Afix 400 mg Tablet
- Treatment of bacterial infections
- Uses include urinary tract infection, tonsillitis, pharyngitis, and bronchitis
- Commonly reported side effects include diarrhea, abdominal pain, dizziness
- Instructions for storage and disposal
- Not suitable for treating cold and flu
- No special dietary instructions
- Not prescribed for treating diarrhea
- Not recommended for infants under 6 months
- Not a penicillin variant
- Known side effect of diarrhea