Arthanib 5 mg (Tablet)
Unit Price: ৳ 48.00 (1 x 10: ৳ 480.00)
Strip Price: ৳ 480.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tofacitinib |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Rheumatoid Arthritis
- Psoriatic Arthritis
- Ulcerative Colitis
Pharmacology
- Autoimmune disease characterized by dysregulation of pro-inflammatory cytokines
- Involvement of cytokine signals, janus kinase signalling pathway, and immune cell function
Dosage & Administration
- Tofacitinib 5 mg twice daily
- Tofacitinib 11 mg once daily
- Recommended dosage in patients with moderate and severe renal impairment or moderate hepatic impairment
Interaction
- Potent inhibitors of Cytochrome P450 3A4 (CYP3A4)
- Moderate inhibition of CYP3A4 and potent inhibition of CYP2C19
- Potent CYP inducers (e.g. Rifampin)
Side Effects
- Upper respiratory tract infections
- Headache
- Diarrhea
- Nasopharyngitis
Pregnancy & Lactation
- Pregnancy Category C
- Excretion in human milk
- Potential risk to the fetus
- Discontinue nursing if necessary
Precautions & Warnings
- Avoid use during active serious infection
- Use with caution in patients at increased risk of gastrointestinal perforations
- Recommended laboratory monitoring
- Avoid use with live vaccines
- Do not initiate if absolute lymphocyte count is below certain levels
Use in Special Populations
- Pediatric use not established
- Higher incidence of serious infection in elderly population
- Dosage adjustment for patients with renal or hepatic impairment
Therapeutic Class
- Immunosuppressant
Storage Conditions
- Store below 30°C
- Protect from light and moisture
- Keep out of the reach of children