Dicliz Plus 20 mg+20 mg (Tablet (Extended Release))

Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00

Medicine Details

Category Details
Generic Pyridoxine hydrochloride doxylamine succinate
Company Aristopharma ltd
Also available as
Dicliz plus 10 mg tablet

Title

  • Doxylamine Succinate & Pyridoxine Hydrochloride Tablets

Categories

  • Medication
  • Anti-emetic drug
  • Nausea & Vomiting treatment
  • Pregnancy Medication
  • Vitamin B6 Supplement

Description

  • Used for the treatment of nausea and vomiting of pregnancy
  • Contains Doxylamine Succinate and Pyridoxine Hydrochloride
  • Indicated for women who do not respond to conservative management
  • Tablets to be taken orally
  • Crosses blood-brain barrier
  • Maximum recommended daily dose is two tablets
  • Should be taken on an empty stomach with a glass of water
  • Contraindicated in women taking monoamine oxidase inhibitors (MAOIs)
  • Contraindicated in women with known hypersensitivity to the ingredients
  • Pregnancy category A medication
  • Caution should be exercised while breastfeeding
  • May cause somnolence
  • Anticholinergic properties can affect activities such as driving or operating heavy machinery
  • Not recommended for use with central nervous system (CNS) depressants including alcohol
  • Storage conditions: Store below 30°C in a dry place protected from light

Dimensions

  • Standard tablet size

Color Options

  • Not applicable

Functions

  • Anti-nausea function
  • Antihistamine action
  • Vestibular system inhibition
  • Muscarinic receptor inhibition
  • Antiemetic properties

Materials

  • Doxylamine Succinate
  • Pyridoxine Hydrochloride
  • Inactive ingredients in the formulation

Technical Specifications

  • Pregnancy category A
  • Extended-release or Delayed Release formulation
  • Should be swallowed whole, not crushed, chewed, or split

Design Elements

  • Tablet form

Usability Features

  • Pregnancy treatment
  • Breastfeeding caution
  • Caution for engaging in activities such as driving

Dosage & Administration

  • Initially take one tablet orally at bedtime
  • If symptoms persist on Day 2, increase the daily dose
  • Maximum recommended dose is two tablets per day
  • Take on an empty stomach with a glass of water
  • Swallow tablets whole
  • Do not crush, chew, or split the tablets
  • Take daily and not on an as needed basis

Interaction

  • Contraindicated with monoamine oxidase inhibitors (MAOIs)
  • Not recommended with alcohol and other CNS depressants

Contraindications

  • Known hypersensitivity to Doxylamine Succinate, other ethanolamine derivative antihistamines, Pyridoxine Hydrochloride or any inactive ingredient in the formulation
  • Monoamine oxidase (MAO) inhibitors intensify and prolong the adverse central nervous system effects of the medication

Side Effects

  • Somnolence
  • Accidents resulting from the combined use with CNS depressants

Pregnancy & Lactation

  • Pregnancy category A
  • Intended for the treatment of nausea and vomiting of pregnancy
  • Excreted into breast milk
  • Caution should be exercised while breastfeeding

Precautions & Warnings

  • May cause somnolence
  • Avoid engaging in activities such as driving or operating heavy machinery
  • Not recommended if concurrently using central nervous system (CNS) depressants including alcohol
  • Use with caution in women with asthma, increased intraocular pressure, narrow angle glaucoma, stenosing peptic ulcer, pyloroduodenal obstruction or urinary bladder-neck obstruction

Overdose Effects

  • Signs and symptoms of intoxication may not be immediately apparent
  • Signs and symptoms may include restlessness, dryness of mouth, dilated pupils, sleepiness, vertigo, mental confusion and tachycardia
  • At toxic doses, exhibits anticholinergic effects including seizures, rhabdomyolysis, acute renal failure, and death
  • Treatment may consist of gastric lavage or activated charcoal, whole bowel irrigation, and symptomatic treatment

Therapeutic Class

  • Anti-emetic drugs

Storage Conditions

  • Store at below 30°C in a dry place protected from light
  • Keep out of reach of children

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