Flutica 0.05% (Cream)
10 gm tube: ৳ 96.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Fluticasone propionate topical |
| Company | Aristopharma ltd |
Indications
- Relief of inflammatory manifestations
- Relief of pruritic manifestations
Pharmacology
- Glucocorticoid
- High topical anti-inflammatory potency
- Low HPA-axis suppressive activity
- Therapeutic index greater than most commonly available steroids
- Selective for glucocorticoid receptor
- Affinity for human glucocorticoid receptors
- Agonist activity at human glucocorticoid receptors
- Weak affinity for progesterone receptor
- Virtually no affinity for mineralocorticoid, estrogen, or androgen receptors
- Half-life of glucocorticoid-receptor complex is approximately 10 hours
Dosage & Administration
- Cream application once daily
- Ointment application twice daily
Interaction
- No information available
Contraindications
- Rosacea
- Acne vulgaris
- Perioral dermatitis
- Primary cutaneous viral infections
- Hypersensitivity to any of the ingredients
- Perianal and genital pruritus
- Not indicated in treatment of primarily infected skin lesions caused by fungi or bacteria
- Not indicated for dermatoses in children under one year of age
Side Effects
- Local burning
- Pruritus
- Signs of hypersensitivity
- Local atrophic changes in the skin
- Thinning of the skin
- Striae
- Dilatation of superficial blood vessels
- Hypertrichosis
- Hypopigmentation
- Secondary infection
- Allergic contact dermatitis
- Exacerbation of signs and symptoms of dermatoses
- Features of hypercorticism
Pregnancy & Lactation
- Consideration during pregnancy based on expected benefit to the mother
- No investigation on excretion into human breast milk
- Plasma levels likely to be low in breastfeeding mothers
- Weigh therapeutic benefits against potential hazards to mother and baby
Precautions & Warnings
- Very low propensity for systemic absorption
- Prolonged application to large areas might lead to adrenal suppression
- Children may absorb larger amounts of topical corticosteroids
- Atrophic changes on the face after prolonged treatment
- Appropriate antimicrobial therapy for treating inflammatory lesions
- Withdrawal of topical corticosteroid therapy for spread of infection
- Bacterial infection encouraged by warm, moist conditions induced by occlusive dressing
Overdose Effects
- Acute overdosage is very unlikely
- Features of hypercorticism in case of chronic overdosage
- Discontinuation of application in case of chronic overdosage or misuse
Therapeutic Class
- Fluticasone & combined preparations topical
Storage Conditions
- Store below 30°C
- Do not freeze