Linaglip-M ER 5 mg+1000 mg (Tablet (Extended Release))
Unit Price: ৳ 20.00 (7 x 4: ৳ 560.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Linagliptin metformin hydrochloride |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Adjunct to diet and exercise
- Improves glycemic control in adults with type 2 diabetes mellitus
Pharmacology
- Inhibits DPP-4 enzyme
- Increases active incretin hormones
- Stimulates insulin release
- Decreases glucagon secretion
- Lowers basal and postprandial glucose levels
- Improves insulin sensitivity
Dosage & Administration
- Individualized dosage based on effectiveness and tolerability
- Maximum recommended dose of 2.5 mg Linagliptin and 1000 mg Metformin Hydrochloride twice daily with meals
- Gradual dose escalation to reduce gastrointestinal side effects
- Recommended starting dose based on prior treatment
Interaction
- Potential interaction with cationic drugs
- Possible interaction with carbonic anhydrase inhibitors
- Interaction with inducers of P-glycoprotein and CYP3A4 enzymes
- Impact of drugs affecting glycemic control
Contraindications
- Contraindicated in renal impairment
- Contraindicated in acute or chronic metabolic acidosis (diabetic ketoacidosis)
- Contraindicated in hypersensitivity to Linagliptin or Metformin Hydrochloride
Side Effects
- Common side effects of nasopharyngitis and diarrhea
- Increased risk of hypoglycemia with sulfonylureas
Pregnancy & Lactation
- Limited data in pregnant women
- Caution advised during pregnancy and lactation
Precautions & Warnings
- Discontinue in case of lactic acidosis or pancreatitis
- Monitoring of Vitamin B12 levels
- Symptoms of lactic acidosis and pancreatitis
- Precautions for alcohol, other medicines, counseling, travel, and emergencies
- Risk of hypoglycemia
- Treatment of low blood sugar symptoms
Overdose Effects
- Usual supportive measures in case of overdose
- Hemodialysis or peritoneal dialysis unlikely to remove Linagliptin
- Hypoglycemia and lactic acidosis reported in overdose cases
Therapeutic Class
- Combination Oral hypoglycemic preparations
Storage Conditions
- Store below 30°C, protected from light and moisture
- Keep out of the reach of children