Nitrocard 400 mcg/spray (Topical Spray)

200 metered spray: ৳ 250.00

Medicine Details

Category Details
Generic Nitroglycerin sublingual spray
Company Aristopharma ltd

Title and Category

  • Nitrocard Sublingual Spray
  • Medicine
  • Coronary Vasodilator

Indications

  • Relief of angina pectoris
  • Prophylaxis of angina pectoris
  • Coronary artery disease

Description

  • Organic nitrate
  • Vasodilator
  • Metered dose spray
  • 400 mcg per spray
  • 200 metered sprays
  • Under the tongue application

Mode of Action

  • Relaxation of vascular smooth muscle
  • Vasodilator effect
  • Reduction of venous return to the heart
  • Reduction of left ventricular enddiastolic pressure
  • Reduction of systemic vascular resistance
  • Reduction of arterial pressure

Dosage

  • 1-2 metered sprays at the onset of an attack
  • Maximum 3 metered sprays within 15 minutes
  • Prophylactic use 5-10 minutes prior to activities

Administration

  • Carry at all times
  • Not for routine use
  • Avoid alcoholic beverages
  • Avoid sildenafil, vardenafil, or tadalafil
  • Keep away from children
  • Sitting down during administration
  • Not shaking the container
  • Administering the spray under the tongue
  • Avoid swallowing immediately after administration
  • Repeat administration if needed

Interaction

  • Severe hypotension and collapse with alcohol
  • Enhanced bioavailability of dihydroergotamine with oral use
  • Orthostatic hypotension with combined use of certain drugs

Contraindications

  • Hypersensitivity to nitrates
  • Hypotension, hypovolaemia, severe anaemia
  • Cerebral haemorrhage, brain trauma, mitral stenosis
  • Angina caused by hypertrophic obstructive cardiomyopathy
  • Concomitant administration of phosphodiesterase inhibitors for erectile dysfunction

Side Effects

  • Headache
  • Facial flushing
  • Dizziness
  • Nausea
  • Vomiting
  • Feelings of weakness
  • Postural hypotension
  • Reflex tachycardia

Pregnancy & Lactation

  • Pregnancy Category C
  • Caution in lactating women

Precautions & Warnings

  • Monitoring hemodynamics and clinical status during acute myocardial infarction
  • Caution in patients with impaired renal or hepatic function, hypothyroidism, malnutrition, or hypothermia

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients

Overdose Effects

  • Severe hypotension
  • Throbbing headache
  • Vertigo
  • Palpitation
  • Visual disturbance
  • Flushing and perspiring skin
  • Nausea and vomiting
  • Syncope
  • Methemoglobinemia
  • Circulatory collapse

Therapeutic Class

  • Nitrates
  • Coronary vasodilators

Storage Conditions

  • Cool and dry place
  • Away from light and heat
  • Keep out of the reach of children

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