Triclean 0.01%+4%+0.05% (Cream)

30 gm tube: ৳ 200.00

Medicine Details

Indications

  • Short-term treatment of moderate to severe melasma of the face
  • Requires avoidance of sun exposure
  • Use of sunscreen with at least SPF 30

Pharmacology

  • Contains Fluocinolone Acetonide, Hydroquinone, and Tretinoin as active ingredients
  • Mechanism of action is unknown
  • Fluocinolone Acetonide is a topical corticosteroid with anti-inflammatory properties
  • Hydroquinone is a depigmenting agent interrupting melanin synthesis
  • Tretinoin is a keratolytic agent

Dosage & Administration

  • Applied once daily at night
  • Applied at least 30 minutes before bedtime
  • Should be applied to hyperpigmented areas including surrounding skin
  • Use of sunscreen and protective clothing during the day
  • Avoidance of sunlight exposure

Interaction

  • Avoid use of medicated or abrasive soaps, cleansers, cosmetics with drying effects
  • Avoid products with high alcohol concentration, astringents, or keratolytic drugs
  • Concomitant use of photosensitizing medications should be avoided

Contraindications

  • History of hypersensitivity, allergy, or intolerance to the product or its components

Side Effects

  • Potential for severe allergic reactions
  • Possible skin reactions such as redness, peeling, burning, dryness, and itching

Pregnancy & Lactation

  • Pregnancy Category C
  • Potential teratogenic effects of tretinoin
  • Limited data on safety during pregnancy
  • Caution in nursing women due to potential systemic absorption

Precautions & Warnings

  • Hydroquinone and Tretinoin may cause mild to moderate irritation
  • Possible local irritation and hypersensitivity reactions
  • Potential for reversible Hypothalamic-Pituitary-Adrenal axis suppression
  • Risk of Cushing's syndrome and hyperglycemia with systemic absorption of corticosteroid

Therapeutic Class

  • Hydroquinone Preparations

Storage Conditions

  • Store in a cool and dry place
  • Protected from light
  • Avoid freezing
  • Keep out of reach of children

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