Naspro Plus 375 mg+20 mg (Tablet (Delayed Release))

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Naproxen sodium esomeprazole magnesium
Company Popular pharmaceuticals ltd
Also available as
Progut n 375 mg tablet Progut n 500 mg tablet Naspro plus 500 mg tablet

Title and Categories

  • Naproxen & Esomeprazole Tablet
  • Medicine
  • Pharmaceutical

Indications

  • Relief of Osteoarthritis
  • Relief of Rheumatoid arthritis
  • Relief of Ankylosing spondylitis
  • Decrease the risk of gastric ulcers

Pharmacology

  • Immediate release Esomeprazole Magnesium layer
  • Enteric-coated Naproxen core
  • Inhibition of prostaglandin synthesis

Dosage

  • Adult dosage
  • Adolescent dosage
  • Dosage with different body weights

Administration

  • To be taken 30 minutes before meals
  • Do not split, chew, crush, or dissolve the tablet

Interaction

  • Reduced antihypertensive effect with ACE inhibitors, diuretics, and beta-blockers
  • Increased risk of bleeding complication with warfarin
  • Interference with absorption of drugs like Ketoconazole and iron salts

Contraindications

  • Known hypersensitivity
  • History of allergic reactions
  • Contraindicated during peri-operative period for CABG surgery

Side Effects

  • Decreased incidence of gastrointestinal side effects
  • Lower risk of arterial thrombotic events with Naproxen
  • Reported adverse events such as nausea, vomiting, diarrhea, and abdominal pain

Pregnancy & Lactation

  • Contraindicated during third trimester of pregnancy
  • Not recommended during breastfeeding
  • May impair female fertility

Precautions & Warnings

  • Avoid use with other NSAIDs
  • Minimize undesirable effects with lowest effective dose
  • Increased frequency of adverse reactions in older people

Use in Special Populations

  • Increased unbound plasma fraction of naproxen in elderly patients
  • Not recommended for use in patients with moderate to severe or severe renal impairment
  • Monitor patients with hepatic impairment closely

Overdose Effects

  • Symptoms of naproxen overdose
  • Symptoms of esomeprazole overdose
  • Management of overdose symptoms

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Store below 30°C
  • Protect from light and moisture
  • Keep out of reach of children

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