Defrol 20000 IU (Capsule)

Unit Price: ৳ 20.00 (1 x 10: ৳ 200.00)
Strip Price: ৳ 200.00

Medicine Details

Indications

  • Prevention of Vitamin D3 deficiency
  • Treatment of Vitamin D3 deficiency
  • Prevention of rickets
  • Prevention of osteomalacia
  • Prevention of osteoporosis
  • Prevention of pre-eclampsia during pregnancy
  • Immunity boost

Pharmacology

  • Active form: Calcitriol
  • Effect on Vitamin D receptors
  • Absorption in small intestine
  • Metabolism in liver and kidney
  • Half-life of about 50 days
  • Storage in fat and muscle
  • Elimination via faeces and urine

Dosage & Administration

  • Adult dosage
  • Children dosage
  • Different dosage forms: capsule, film-coated tablet, oroflash or chewable tablets, syrup, injection
  • Timing of administration: with food or after a meal
  • Dosage for specific therapy for osteoporosis
  • Dosage for patients with risk of Cholecalciferol deficiency
  • Dosage for Cholecalciferol deficient patients

Interaction

  • Drugs causing Vitamin D3 deficiencies
  • Drugs increasing the need for Vitamin D3

Contraindications

  • Diseases associated with hypercalcaemia
  • Hypersensitivity to Vitamin D3
  • Evidence of Vitamin D3 toxicity

Side Effects

  • Anorexia
  • Lassitude
  • Nausea & vomiting
  • Diarrhea
  • Constipation
  • Weight loss
  • Polyuria
  • Sweating
  • Headache
  • Thirst
  • Vertigo
  • Raised concentrations of calcium and phosphate in plasma and urine

Pregnancy & Lactation

  • Safe use during pregnancy
  • Excretion in breast milk
  • Recommended daily intake for pregnant women
  • Excretion in breast milk

Precautions & Warnings

  • Monitoring plasma-calcium concentration
  • Consultation before supplementation with specific medications
  • Consultation for certain medical conditions

Use in Special Populations

  • Lack of established safety & efficacy in children under 12 years

Overdose Effects

  • Hypervitaminosis D

Therapeutic Class

  • Vitamin in bone formation
  • Vitamin-D preparations

Storage Conditions

  • Temperature below 30°C
  • Protection from light & moisture
  • Keep out of the reach of children

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