Defrol 40000 IU (Capsule)

Unit Price: ৳ 35.00 (1 x 10: ৳ 350.00)
Strip Price: ৳ 350.00

Medicine Details

Indications

  • Prevention of rickets
  • Treatment of osteoporosis
  • Prevention of osteomalacia
  • Supports bone and teeth health
  • Boosts immunity

Pharmacology

  • Active form: Calcitriol
  • Binds to Vitamin D receptors
  • Fat soluble with a half life of 50 days
  • Absorbed in small intestine
  • Metabolized to 25-hydroxy Vitamin D3 (Calcidiol)

Dosage & Administration

  • Doses for adults and children
  • Different dosages for capsules, film-coated tablets, oroflash/chewable tablets, syrup, and injection
  • Timing of administration with or without food

Interaction

  • Interference with absorption and metabolism by certain drugs
  • Increased need due to corticosteroid use

Contraindications

  • Hypercalcaemia
  • Hypersensitivity to Vitamin D3
  • Evidence of Vitamin D3 toxicity

Side Effects

  • Anorexia
  • Nausea & vomiting
  • Diarrhea
  • Constipation
  • Sweating
  • Headache
  • Thirst

Pregnancy & Lactation

  • Safe use during pregnancy up to 4000 IU
  • Excretion in breast milk
  • Practitioner's advice for dose adjustments in deficiency

Precautions & Warnings

  • Monitoring plasma-calcium concentration
  • Consultation for patients with specific conditions or using certain medications

Use in Special Populations

  • Safety & efficacy not established in children under 12 years

Overdose Effects

  • Hypervitaminosis D

Therapeutic Class

  • Vitamin in bone formation
  • Vitamin-D preparations

Storage Conditions

  • Temperature and light/moisture protection
  • Keep out of the reach of children

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