Don-A 10 mg (Tablet)
Unit Price: ৳ 3.45 (10 x 14: ৳ 483.00)
Strip Price: ৳ 48.30
Medicine Details
Category | Details |
---|---|
Generic | Domperidone maleate |
Company | Acme laboratories ltd |
Also available as |
Product Title
- Don-A 10 mg Tablet
Product Category
- Medicine
- Gastrointestinal Health
- Nausea and Vomiting Relief
- Parkinson's Disease Treatment
Product Description
- Dopamine antagonist medication
- Treats nausea and vomiting
- Helps relieve dyspeptic symptom complex
- Facilitates gastric emptying
- Enhances antral and duodenal peristalsis
- Regulates contraction of the pylorus
- Increases esophageal peristalsis
- Restores normal motility and tone of the upper gastrointestinal tract
Ingredients
- Domperidone
- Chemical Structure: C22H24ClN5O2
Dosage & Administration
- Recommended oral dose for adults: 10-20 mg every 6-8 hours daily
- Recommended oral dose for children: 2-4 ml suspension/10 kg body weight
- Recommended rectal dose for adults: 30-60 mg every 4-8 hours
Indications
- Dyspeptic symptom complex relief
- Acute nausea and vomiting treatment
- Treatment of nausea and vomiting induced by radiotherapy or drug therapy
Contraindications
- Known hypersensitivity to Domperidone
- Neonates
- Gastrointestinal hemorrhage
- Mechanical obstruction or perforation
- Prolactin releasing pituitary tumor
Side Effects
- Transient intestinal cramps
- Extrapyramidal phenomena
- Increase in plasma prolactin level
- Rare allergic reactions such as rash and urticaria
Pregnancy & Lactation
- Should be used with caution during the first trimester of pregnancy
- Excreted in breast milk of lactating rats
- Not recommended for nursing mothers
Precautions & Warnings
- Absolute caution in the case of children
- Increased risk of extra-pyramidal reactions in young children
- Caution in patients with hepatic impairment
Use in Special Populations
- Use in infants with great caution and under close medical supervision
- Caution in patients with hepatic impairment
- Dosing frequency adjustment in patients with severe renal insufficiency
Overdose Effects
- Drowsiness
- Disorientation
- Extrapyramidal reactions
Interaction
- Anticholinergic drugs may antagonize the antidyspeptic effect of Domperidone
- Lower oral bioavailability with simultaneous administration of antacids and antisecretory drugs
- Potential drug interactions with CYP3A4 inhibitors
- Influence on the absorption of concomitantly orally administered drugs
Therapeutic Class
- Motility Stimulants
- Dopamine antagonist
- Prokinetic drugs
Storage Conditions
- Store below 30°C
- Protected from light & moisture
- Keep out of children's reach
Chemical Structure
- Molecular Formula: C22H24ClN5O2
- Chemical Structure Image: See chemical structure image link
Common Questions
- Used to treat nausea and vomiting
- Should be taken before meals as per prescribed dose and duration
- May cause dizziness and sleepiness
- Avoid consuming alcohol during medication
- Dry mouth may occur as a side effect
- Do not take for longer than 7 days without consulting a doctor