Ranidin 50 mg/2 ml (IM/IV Injection)
2 ml ampoule: ৳ 10.03 (2 x 5: ৳ 100.30)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Treatment & prevention of ulcer associated with non-steroidal anti-inflammatory agent
- Post operative stress ulcer
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease (GERD)
Pharmacology
- Competitively blocks histamine at H2-receptors
- Inhibits gastric acid secretion
Dosage & Administration
- Usual dosage is 150 mg twice daily for 4 to 8 weeks
- Dosage for reflux oesophagitis: 150 mg twice daily or 300 mg at bedtime for up to 8 weeks
- Dosage for Zollinger-Ellison syndrome: 150 mg 3 times daily
- Recommended oral dose for the treatment of peptic ulcer in children is 2 mg/kg to 4 mg/kg twice daily
- Dosage for IV injection & IV Infusion
Interaction
- Delayed absorption and increased peak serum concentration with propantheline bromide
- Minimally inhibits hepatic metabolism of certain drugs
- May alter absorption of pH-dependent drugs
- May reduce bioavailability with antacids
Contraindications
- Hypersensitivity to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy & Lactation
- Ranitidine crosses the placenta
- Excreted in human breast milk
- Caution should be exercised when administered to a nursing mother
Precautions & Warnings
- Reduced dosage for patients with impaired renal and hepatic function
Use in Special Populations
- Similar ulcer healing rates in elderly patients
- No difference in adverse effects incidence between elderly and younger patients
Overdose Effects
- Specific in action, no particular problems expected
- Symptomatic and supportive therapy may be given if necessary
Therapeutic Class
- H2 receptor antagonist
Reconstitution
- Instructions for reconstitution for different administration methods
Storage Conditions
- Store in a cool and dry place
- Protect from light