Hemotrax 500 mg (Tablet)
Unit Price: ৳ 20.00 (2 x 10: ৳ 400.00)
Strip Price: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tranexamic acid |
| Company | Unimed unihealth pharmaceuticals ltd |
| Also available as |
Indications
- Prophylaxis and therapy of hemophtoes
- Digestive hemorrhages
- Hemorrhagic syndromes in leukaemia
- Cirrhosis and hemophilia
- Thrombocytopenic purpura
- Accidents during thrombolytic therapy and transfusion
- Antihemorrhagic therapy during operations of any type and nature
- Prophylaxis and antihemorrhagic therapy of prostatic, vesical and renal surgery
- Prophylaxis and therapy of post-partum and puerperium hemorrhages
- Hemorrhagic metrophathies and functional menometrorrhagias
- Prophylaxis and antihemorrhagic therapy during tonsillectomy
- Prophylaxis and antihemorrhagic therapy during maxillofacial operations
- To promote the formation of a fibrin capsule to inhibit the growth of ovarian tumors
- Interaction with Streptokinase & Urokinase
- Known individual hypersensitivity to the product
Pharmacology
- Preparation of tranexamic acid
- Antifibrinolytic action
- Inhibition of plasminogen activation
- Low acute toxicity
- Well absorbed by oral route
- Excretion mainly by renal route
- No interference with clotting processes
- No tendency to thrombophilia
Dosage & Administration
- Usual adult dose: 500-1000 mg 3 times daily
- Mean recommended daily doses for prophylaxis: 0.5-1 gm orally, 500 mg by parenteral route
- Therapeutic oral dose increases to 1-3 gm
- Oral administration effect seen 15-30 minutes after
- Intravenous and intramuscular treatment for children
- No dosage reduction in elderly patients
Interaction
- Incompatibility with solutions containing penicillins
- Antagonism with thrombolytic drugs
- Potential for increased thrombus formation with estrogen containing drugs
- Avoid direct admixture with whole blood during transfusion
Contraindications
- Thromboembolic disease
- Arterial and venous thrombosis
- Endocavitary hemorrhages
- Serious kidney failure
Side Effects
- Sense of fatigue
- Conjunctival irritation
- Nasal blockage
- Nausea
- Diarrhea
- Gastric pyrosis
- Postural hypotension
Pregnancy & Lactation
- Should not be administered during known and presumed pregnancy
- Passes into breast milk at a low concentration
Precautions & Warnings
- Use in cases where there is hyperfibrinolysis
- Prophylactic treatment must begin 24 hours before operation
- Therapy of hemorrhages must be prolonged for at least 24 hours after manifestations have disappeared
- Reduce doses in hematuria
- Caution in subjects with renal or hepatic issues
Therapeutic Class
- Anti-fibrinolytic drugs
- Haemostatic drugs
Storage Conditions
- Dry place at 15-30°C
- Away from light
- Keep out of children's reach