Utrogestan 200 mg (Capsule)

Unit Price: ৳ 72.00 (15's pack: ৳ 1,080.00)

Medicine Details

Category Details
Generic Progesterone micronized capsule
Company Besins manufacturing belgium
Also available as
Utrogestan 100 mg capsule

Usable for

  • Maintenance of Pregnancy in cases of Threatened / Recurrent abortion
  • Luteal support during IUI and ART procedures IVF-ET
  • Luteal support in cases of proven luteal phase insufficiency
  • Post-menopausal hormone replacement therapy (HRT) either in sequential or in continuous regimen
  • Prevention of endometrial hyperplasia where endogenous estrogen is present
  • Progesterone challenge test in secondary amenorrhoea
  • Cycle control along with estrogen therapy
  • Dysfunctional uterine bleeding (DUB)
  • Premenstrual tension
  • Endometriosis
  • Oocyte donation programme
  • Benign mastopathy

Pharmacology

  • Contains micronised progesterone
  • Biologically identical to natural endogenous progesterone
  • Increases bioavailability of progesterone
  • Maximal serum progesterone levels increased after meals
  • Metabolized to pregnanediols and pregnanolones in the liver
  • Approximately 96%-99% bound to serum proteins

Dosage & Administration

  • Recommended dose: Progesterone 100 mg/200 mg 2 to 3 soft gel capsules daily
  • Flexible dosage regimen depending on the indication and patient requirements
  • Specific dosage for different indications such as Maintenance of Pregnancy, In-vitro fertilization, HRT, Oocyte donation program, Luteal support, Luteal phase insufficiency, Secondary amenorrhoea, Premenstrual syndrome, Benign mastopathy

Interaction

  • Inhibition of progesterone metabolism by Ketoconazole

Contraindications

  • Hypersensitivity
  • Hepatic dysfunction
  • Undiagnosed vaginal bleeding
  • Porphyria
  • Cancers of uterus and genital organs
  • Breast cancers
  • History of stroke or blood clots
  • Miscarriage and tissue left in the uterus

Side Effects

  • Devoid of estrogenic, androgenic and mineralocorticoid effects
  • Reported mild somnolence and other CNS side effects like depression, breast tenderness and bloating

Precautions & Warnings

  • Severe renal insufficiency
  • Diabetes mellitus
  • Seizures
  • Migraine
  • Headache
  • Heart diseases
  • Depression

Therapeutic Class

  • Drugs for menopausal symptoms
  • Hormone replacement therapy
  • Female Sex hormones
  • Oral Contraceptive preparations

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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