Linaptin M 2.5 mg+500 mg (Tablet)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Title

  • Linagliptin & Metformin Hydrochloride Combination Tablet

Categories

  • Medicine
  • Diabetes Management
  • Oral Hypoglycemic Preparations

Description

  • Indicated as an adjunct to diet and exercise for adults with type 2 diabetes mellitus
  • Improves glycemic control through inhibition of DPP-4 enzyme and reduction of hepatic glucose production

DosageAndAdministration

  • Individualized dosage based on effectiveness and tolerability
  • Maximum recommended dose of 2.5 mg Linagliptin and 1000 mg Metformin Hydrochloride twice daily with meals
  • Dose escalation should be gradual to reduce gastrointestinal side effects
  • Immediate release and extended release tablet options available

Interaction

  • Potential interaction with cationic drugs, carbonic anhydrase inhibitors, inducers of P-glycoprotein and CYP3A4 enzymes, and drugs affecting glycemic control

Contraindications

  • Contraindicated in renal impairment, metabolic acidosis, and hypersensitivity to either component

SideEffects

  • Common side effects include nasopharyngitis and diarrhea
  • Increased risk of hypoglycemia with sulfonylureas

PregnancyAndLactation

  • Limited data; caution advised during pregnancy and lactation

PrecautionsAndWarnings

  • Discontinue immediately in case of lactic acidosis or suspected pancreatitis
  • Monitoring of Vitamin B12 levels may be required due to Metformin use
  • Careful monitoring and precautions for lactic acidosis symptoms

OverdoseEffects

  • Supportive measures for overdose include removal of unabsorbed material, clinical monitoring, and supportive treatment
  • Metformin is dialyzable in case of overdose

TherapeuticClass

  • Oral hypoglycemic preparations

StorageConditions

  • Store below 30°C, protected from light and moisture, keep out of the reach of children

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