Linaptin M 2.5 mg+850 mg (Tablet)

Unit Price: ৳ 14.00 (5 x 4: ৳ 280.00)

Strip Price: ৳ 56.00

Medicine Details

Category	Details
Generic	Linagliptin metformin hydrochloride
Company	General pharmaceuticals ltd
Also available as	Linaptin m 25 mg tablet

Indications

Adjunct to diet and exercise
Improves glycemic control
Type 2 diabetes mellitus

Pharmacology

Inhibitor of DPP-4 enzyme
Increases active incretin hormone concentrations
Stimulates insulin release
Decreases glucagon secretion
Biguanide type oral antihyperglycemic drug
Lowers plasma glucose
Improves insulin sensitivity
Decreases hepatic glucose production

Dosage & Administration

Maximum recommended dose: 2.5 mg Linagliptin and 1000 mg Metformin Hydrochloride
Gradual dose escalation
Immediate release tablet
Extended release tablet
Individualized dosage based on effectiveness and tolerability

Interaction

Cationic Drugs
Carbonic Anhydrase Inhibitors
Inducers of P-glycoprotein and CYP3A4 Enzymes
Drugs Affecting Glycemic Control

Contraindications

Renal impairment
Metabolic acidosis
Hypersensitivity to components

Side Effects

Nasopharyngitis
Diarrhea
Hypoglycemia

Pregnancy & Lactation

Use during pregnancy if clearly needed
Caution during lactation

Precautions & Warnings

Lactic acidosis
Pancreatitis
Radiologic studies precautions
Monitoring Vitamin B12 levels
Symptoms of lactic acidosis
Alcohol consumption precautions
Other medicines precautions
Counseling
Travel recommendations
Emergency preparedness
Hypoglycemia symptoms
Treatment of low blood sugar symptoms

Overdose Effects

Supportive measures for overdose
Clinical monitoring
Hemodialysis or peritoneal dialysis for Metformin overdose
No dose-related clinical adverse drug reactions with Linagliptin overdose

Therapeutic Class

Combination Oral hypoglycemic preparations

Storage Conditions

Cool & dry place
Protected from light & moisture
Below 30°C
Keep out of the reach of children

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