Methipred 1 gm/vial (IM/IV Injection)

1 gm vial: ৳ 1,000.00

Medicine Details

Category	Details
Generic	Methylprednisolone sodium succinate
Company	General pharmaceuticals ltd
Also available as	Methipred 500 mg injection

Indications

Endocrine disorder
Rheumatic disorder
Collagen disease
Dermatological disease
Allergic states
Ophthalmic disease
Gastrointestinal disease
Respiratory disease
Hematologic disorder
Neoplastic disease
Edematous state
Miscellaneous

Pharmacology

Glucocorticoid
Anti-inflammatory effects
Salt-retaining properties
Potent anti-inflammatory effects
Excretion within 12 hours
Influence on metabolism and electrolyte balance
Suppressive effect on the immune response

Dosage & Administration

IM or IV administration
Intravenous injection
High dose therapy
Shock treatment
Maintenance therapy
Variable initial dosage
Pediatric dosage
Treatment of multiple sclerosis exacerbations
Intravenous infusion

Interaction

Aminoglutethimide
Amphotericin B interaction
Macrolide antibiotics interaction
Anticholinesterases interaction
Anticoagulants interaction
Antidiabetics interaction
Antitubercular drugs interaction
Cyclosporine interaction
Digitalis glycosides interaction
Estrogens interaction
Hepatic Enzyme Inhibitors interaction
Ketoconazole interaction
NSAIDs interaction
Skin tests suppression
Vaccines response suppression

Contraindications

Systemic fungal infections
Hypersensitivity
Intrathecal administration
Idiopathic thrombocytopenic purpura

Side Effects

Fluid and Electrolyte Disturbances
Musculoskeletal effects
Gastrointestinal effects
Dermatologic effects
Neurological effects
Endocrine effects
Ophthalmic effects
Others
Parenteral corticosteroid therapy side effects

Pregnancy & Lactation

Teratogenic in many species
No adequate and well-controlled studies
Corticosteroids in breast milk
Observation for hypoadrenalism in infants
Risk-benefit decision for use during pregnancy

Precautions & Warnings

Heat sensitivity
Lowest possible dose usage
Gradual reduction in dosage
Complications dependent on dose and duration of treatment
Regular monitoring during prolonged therapy

Use in Special Populations

Pediatric Use
Geriatric Use
Growth effects in pediatric patients
Cautious dose selection for elderly patients

Overdose Effects

Supportive and symptomatic therapy
Temporary dose reduction for chronic overdosage
Introduction of alternate day treatment for chronic overdosage

Therapeutic Class

Glucocorticoids

Reconstitution

Removal of protective seal
Aseptic addition of Water for Injection BP
Agitation for solution
Injection withdrawal

Storage Conditions

Protection from light
Controlled room temperature storage
Use within 48 hours after mixing

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