Ramil 2.5 mg (Tablet)
Unit Price: ৳ 5.02 (5 x 10: ৳ 251.00)
Strip Price: ৳ 50.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Ramipril |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Product Title
- Ramil
Categories
- Hypertension Medication
- Heart Failure Medication
- Cardiovascular Medication
- ACE Inhibitor
Description
- Ramil is indicated for the management of hypertension, congestive heart failure, treatment of patients after myocardial infarction, prevention of major cardiovascular events, and reduction of the risk of stroke, myocardial infarction, and death from cardiovascular events. It is available in tablet form and is long-acting and well-tolerated for long-term therapy.
Dosage Range
- 1.25-20 mg daily
Color Options
- Not Applicable
Active Ingredient
- Ramipril
Pharmacological Action
- Angiotensin Converting Enzyme (ACE) Inhibitor
Administration Method
- Oral
Interaction
- Contraindicated with diuretics, lithium, alcohol, NSAIDs, sacubitril/valsartan, aliskiren-containing medicines, and angiotensin II receptor antagonists
Contraindications
- Hypersensitivity to ramipril or any other ACE inhibitor
- History of angioedema
- Concomitant use with sacubitril/valsartan therapy
- Haemodynamically relevant renal artery stenosis
- Hypotensive or haemodynamically unstable states
- Aliskiren-containing medicines in patients with diabetes or moderate to severe renal impairment
- Angiotensin II receptor antagonists (AIIRAs) in patients with diabetic nephropathy
- During pregnancy
Side Effects
- Dizziness
- Headache
- Fatigue
- Asthenia
- Symptomatic hypotension
- Cough
- Nausea
- Vomiting
- Diarrhoea
- Rash
- Urticaria
- Oliguria
- Anxiety
- Amnesia
- Angioneurotic oedema
- Anaphylactic reactions
- Hyperkalaemia
Pregnancy & Lactation
- Contraindicated during pregnancy, should be avoided during breastfeeding
Precautions & Warnings
- Use with caution in patients with impaired renal function, hyperkalaemia, hypotension, and impaired hepatic function
Special Populations
- Elderly: Reduced initial dose may be necessary
- Hepatic impairment: Initiate treatment under close medical supervision
- Renal impairment: Adjust dosage based on creatinine clearance
- Patients pretreated with a diuretic: Consider discontinuation or reduction of diuretic dose
Storage Conditions
- Store at 30°C or below, protect from light, and keep out of the reach of children
Therapeutic Class
- ACE Inhibitor
Indications
- Management of hypertension
- Congestive heart failure
- Treatment after myocardial infarction
- Prevention of major cardiovascular events
- Risk reduction of stroke, myocardial infarction, and death from cardiovascular events
Pharmacology
- Blocks the conversion of angiotensin I to angiotensin II, leading to decreased vasopressor activity and decreased aldosterone secretion
Usability Features
- Long-acting
- Well-tolerated for long-term therapy
Dosage Adjustment
- Based on patient tolerance and response
Drug Overdose Effects
- Excessive peripheral vasodilatation
- Marked hypotension
- Bradycardia
- Electrolyte disturbances
- Renal failure
Management of Overdose
- Primary detoxification by gastric lavage, administration of adsorbents, sodium sulfate; administration of α1-adrenergic agonists, volume, and salt substitution
Administration Instructions
- Tablets must be swallowed with sufficient liquid, must not be chewed or crushed
Interactions Note
- May lead to serious hypotension and hyperkalemia with diuretics
- May increase serum lithium concentration with lithium
- May reduce antihypertensive effect and cause deterioration of renal function with NSAIDs
- May affect the ability to drive and operate machinery
Technical Specifications
- Available in tablet form