Unifylin 100 mg/5 ml (Syrup)
100 ml bottle: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Doxophylline |
| Company | General pharmaceuticals ltd |
| Also available as |
Indications
- Bronchial asthma
- Bronchospasm
- Chronic obstructive pulmonary disease (COPD)
- Pulmonary disease with spastic bronchial component
Pharmacology
- Novel bronchodilator
- Selective inhibition of phosphodiesterase 4
- Relaxes bronchial smooth muscle
- Decreased affinities toward adenosine A1 and A2 receptors
Dosage & Administration
- Elderly dosage: 200 mg tablet two or three times daily
- Adults dosage: 400 mg tablet two or three times daily
- Children dosage: varies based on age and body weight
- Doxophylline SR tablet for required daily dose of 400 mg
Interaction
- Not to be administered with other xanthine preparations
- Limit consumption of caffeine-containing beverages and food
- Caution with ephedrine or sympathomimetic drugs
- Concurrent administration with certain drugs may affect hepatic clearance
Contraindications
- Hypersensitivity to the drug or other xanthine derivatives
- Acute myocardial infarction
- Hypotension
- Lactation
Side Effects
- Nausea
- Vomiting
- Epigastric pain
- Headache
- Irritability
- Insomnia
- Tachycardia
- Tachypnea
- Hyperglycemia
- Albuminuria
- Severe cardiac arrhythmias
- Tonic-clonic seizure
Pregnancy & Lactation
- Animal tests suggest no interference with pre and postnatal growth
- Use during pregnancy to be evaluated case by case
- Contraindicated during lactation
Precautions & Warnings
- Factors affecting hepatic clearance
- Caution in patients with cardiac disease, hypertension, hypoxemia, hyperthyroidism
- Monitoring blood levels in certain conditions
- Slow clearance in congestive heart failure patients
- No risk of addiction or dependence
Overdose Effects
- Severe cardiac arrhythmias
- Tonic-clonic seizure
- Symptomatic treatment of cardiovascular collapse
Therapeutic Class
- Bronchodilator
- Methyl xanthine derivatives
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children
- To be used only on prescription of specialist physician