Ebamine 5 mg/5 ml (Syrup)
Medicine Details
Category | Details |
---|---|
Generic | Ebastine |
Company | Ibn sina pharmaceuticals ltd |
Also available as |
Indications
- Seasonal and Perennial Allergic Rhinitis
- Chronic Idiopathic Urticaria
Pharmacology
Long-acting and selective H1-histamine receptor antagonist. Rapid absorption with extensive first-pass metabolism. Conversion to the active acid metabolite, carebastine.
Dosage & Administration
- Tablet:
- Adults (more than 12 years of age): 10 mg (one tablet) once daily
- Children (6-12 years of age): 5 mg (half tablet) once daily
- Syrup:
- Children (2-5 years of age): 2.5 ml once daily (upto 5 ml in severe cases such as Perennial Allergic Rhinitis)
- Children (6-12 years of age): 5 ml once daily (upto 10 ml in severe cases such as Perennial Allergic Rhinitis)
- Administration Note: May be taken with or without food
Interaction
Increased plasma levels and prolonged QTc interval in combination with ketoconazole or erythromycin. No interaction with theophylline, warfarin, cimetidine, diazepam or alcohol. Enhanced sedation effect of alcohol and diazepam.
Contraindications
Known hypersensitivity to Ebastine or any of its ingredients
Side Effects
- Headache
- Dry mouth
- Drowsiness
- Abdominal pain
- Dyspepsia
- Nausea
- Insomnia
Overdose Effects
No clinically meaningful signs or symptoms observed up to 100 mg. No specific antidote. In case of accidental overdoses, gastric lavage, monitoring of vital functions including ECG, and symptomatic treatment.
Therapeutic Class
Non-sedating antihistamines
Storage Conditions
Store below 30°C at a cool and dry place, away from light. Keep out of reach of children