Doxoma 200 mg (Tablet)

Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00

Medicine Details

Category Details
Generic Doxophylline
Company Drug international ltd
Also available as
Doxoma 400 mg tablet Doxoma 100 mg syrup

Indications

  • Bronchial asthma
  • Bronchospasm
  • Chronic obstructive pulmonary disease (COPD)
  • Pulmonary disease with spastic bronchial component

Pharmacology

  • Selective inhibition of phosphodiesterase 4
  • Relaxation of bronchial smooth muscle
  • Inhibition of platelet activating factor (PAF)
  • Decreased affinities toward adenosine A1 and A2 receptors

Dosage & Administration

  • 200 mg tablet for elderly two or three times daily
  • 400 mg tablet for adults two or three times daily
  • 400 mg daily dose to be taken as a sustained-release tablet
  • 10 ml syrup for children above 12 years
  • 6-9 mg/kg body weight for children 6-12 years

Interaction

  • Not to be administered with other xanthine preparations
  • Limit consumption of caffeine-containing beverages and food
  • Caution with ephedrine or other sympathomimetic drugs
  • Concurrent administration may affect hepatic clearance

Contraindications

  • Hypersensitivity to the drug or other xanthine derivatives
  • Acute myocardial infarction
  • Hypotension
  • During lactation

Side Effects

  • Nausea
  • Vomiting
  • Epigastric pain
  • Headache
  • Insomnia
  • Tachycardia
  • Hyperglycemia

Pregnancy & Lactation

  • Animal tests show no interference with pre and postnatal growth
  • Use during pregnancy should be evaluated on risk-benefit ratio
  • Contraindicated during lactation
  • Does not affect ability to drive or use machines

Precautions & Warnings

  • Factors reducing hepatic clearance may increase plasma levels
  • Caution in patients with cardiac disease, hypertension, or renal impairment

Overdose Effects

  • Severe cardiac arrhythmias
  • Tonic-clonic seizure
  • Discontinuation may be required

Therapeutic Class

  • Bronchodilator
  • Methyl xanthine derivatives

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children
  • Use only on prescription of specialist physician

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