Dsec 30 mg (Capsule (Enteric Coated))

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Dexlansoprazole
Company Drug international ltd
Also available as
Dsec 60 mg capsule

Indications

  • Healing of Erosive Esophagitis
  • Maintenance of Healed Erosive Esophagitis
  • Symptomatic Non-Erosive Gastroesophageal Reflux Disease

Dosage

  • 30 mg Once daily for Maintenance of Healed erosive esophagitis and relief of heartburn
  • 30 mg Once daily for Symptomatic Non-Erosive GERD
  • 60 mg Once daily for Healing of erosive esophagitis

Administration

Can be taken without regard to food. Alternatively, can be opened and granules can be sprinkled on one tablespoon and swallowed immediately.

Mode of Action

Suppresses gastric acid secretion by specific inhibition of the (H+/K+)-ATPase in the gastric parietal cell.

Pharmacology

R-enantiomer of lansoprazole, supplied as a Dual Delayed Release (DDR) formulation in a capsule for oral administration.

Interactions

  • Atazanavir
  • Warfarin
  • Tacrolimus
  • Clopidogrel
  • Methotrexate

Contraindications

Contraindicated in patients with known hypersensitivity to any component of the formulation

Side Effects

  • Diarrhea
  • Abdominal pain
  • Nausea
  • Vomiting
  • Flatulence

Pregnancy & Lactation

Pregnancy Category B. No adequate and well-controlled studies with Dexlansoprazole in pregnant or lactating women.

Precautions & Warnings

  • Gastric Malignancy
  • Clostridium difficile Associated Diarrhea
  • Bone fracture
  • Hypomagnesemia
  • Concomitant use with Methotrexate

Use in Special Populations

  • Safety and effectiveness in patients below 12 years age have not been established
  • No dose adjustment is necessary for elderly patients
  • No dose adjustment for patients with renal impairment
  • No dose adjustment for patients with mild hepatic impairment
  • Maximum daily dose of 30 mg for patients with moderate hepatic impairment

Overdose Effects

No reports of significant overdose. Multiple doses of 120 mg and a single dose of 300 mg did not result in death or severe adverse events.

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Store below 30°C temperature & in a dry place, protected from light. Keep out of reach of children.

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