Ramilon 2.5 mg (Tablet)

Unit Price: ৳ 4.00 (30's pack: ৳ 120.00)

Medicine Details

Category Details
Generic Ramipril
Company Virgo pharmaceuticals ltd
Also available as

Indications

  • Hypertension
  • Congestive heart failure
  • Acute myocardial infarction treatment
  • Glomerular or incipient nephropathy treatment
  • Reduction in cardiovascular risk

Pharmacology

Angiotensin converting enzyme (ACE) inhibitor

Dosage

  • Initial dose 1.25-2.5 mg for hypertension
  • Initial dose 2.5 mg twice daily for congestive heart failure after myocardial infarction
  • Recommended dose 2.5 mg once daily for prevention of major cardiovascular events

Administration

Tablets to be swallowed with liquid, not to be chewed or crushed

Interaction

  • Contraindicated with diuretics
  • May increase serum lithium concentration when used with lithium
  • May be affected by alcohol and NSAIDs

Contraindications

  • Hypersensitivity to ramipril or any other ACE inhibitor
  • History of angioedema
  • Concomitant sacubitril/valsartan therapy
  • Renal artery stenosis
  • Hypotensive or haemodynamically unstable states
  • Concomitant aliskiren-containing medicines in patients with diabetes or moderate to severe renal impairment
  • Concomitant angiotensin II receptor antagonists (AIIRAs) in diabetic nephropathy
  • During pregnancy

Side Effects

  • Dizziness
  • Headache
  • Fatigue
  • Asthenia
  • Hypotension
  • Cough
  • Nausea
  • Vomiting
  • Diarrhoea
  • Rash
  • Urticaria
  • Oliguria
  • Anxiety
  • Amnesia
  • Angioneurotic oedema
  • Anaphylactic reactions
  • Hyperkalaemia

Pregnancy & Lactation

Not recommended during pregnancy or breastfeeding

Precautions & Warnings

  • Use with caution in impaired renal function
  • Use with caution in hyperkalaemia
  • Use with caution in hypotension
  • Use with caution in impaired hepatic function

Use in Special Populations

  • Elderly: consider reduced initial dose
  • Hepatic impairment: initiate treatment under close medical supervision
  • Renal impairment: consider reduced initial dose based on creatinine clearance

Overdose Effects

  • Excessive peripheral vasodilatation
  • Hypotension
  • Bradycardia
  • Electrolyte disturbances
  • Renal failure

Therapeutic Class

Angiotensin-converting enzyme (ACE) inhibitors

Storage Conditions

Store at 30°C or below, protect from light, do not use after expiry date

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