AB Kit 200 mg+200 mcg (Tablet)
(1+4) tablet kit: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Mifepristone misoprostol |
| Company | Renata limited |
Indications
- Early Menstrual Regulation (MR)
- Termination of pregnancy up to 9 weeks (63 days) of gestation
Composition
- Each box contains 2 blister strips
- One strip contains 1 tablet of Mifepristone INN 200 mg
- Another strip contains 4 tablets of Misoprostol USP 200 microgram each
Pharmacology
- Mifepristone is a synthetic steroid with anti-progestational activity
- Misoprostol is a synthetic analogue of prostaglandin E1
Dosage & Administration
- First visit: Mifepristone administration
- Second visit: Misoprostol administration
- Third visit: Post-treatment examination
Interaction
- Mifepristone metabolism may be inhibited by Ketoconazole, Itraconazole, Erythromycin, and grapefruit juice
Contraindications
- History of allergy or known hypersensitivity to Mifepristone or Misoprostol
- Confirmed or suspected ectopic pregnancy
- Chronic adrenal failure
- Haemorrhagic disorders or concurrent anticoagulant therapy
Side Effects
- Nausea
- Vomiting
- Diarrhoea
- Pelvic pain
- Fainting
- Headache
- Dizziness
Pregnancy & Lactation
- Mifepristone is indicated for Menstrual Regulation (MR)
- Mifepristone effects on infants are unknown
- Misoprostol should not be administered to nursing mothers
Precautions & Warnings
- Combination of Mifepristone & Misoprostol should not be given to anyone else
- Intra Uterine Device [IUD] should be removed before treatment with Mifepristone begins
Use in Special Populations
- Patients with hepatic disease should receive a decreased dose of Misoprostol
- No routine dosage adjustment is recommended in older patients or patients with renal impairment
Overdose Effects
- Signs of adrenal failure in case of massive Mifepristone overdose
- Symptoms like sedation, tremor, convulsions, and dyspnea may indicate Misoprostol overdose
Therapeutic Class
- Drugs acting on the Uterus
- Prostaglandin analogues
Storage Conditions
- Store in a cool and dry place, protected from light