AB Kit 200 mg+200 mcg (Tablet)

(1+4) tablet kit: ৳ 300.00

Medicine Details

Category Details
Generic Mifepristone misoprostol
Company Renata limited

Indications

  • Early Menstrual Regulation (MR)
  • Termination of pregnancy up to 9 weeks (63 days) of gestation

Composition

  • Each box contains 2 blister strips
  • One strip contains 1 tablet of Mifepristone INN 200 mg
  • Another strip contains 4 tablets of Misoprostol USP 200 microgram each

Pharmacology

  • Mifepristone is a synthetic steroid with anti-progestational activity
  • Misoprostol is a synthetic analogue of prostaglandin E1

Dosage & Administration

  • First visit: Mifepristone administration
  • Second visit: Misoprostol administration
  • Third visit: Post-treatment examination

Interaction

  • Mifepristone metabolism may be inhibited by Ketoconazole, Itraconazole, Erythromycin, and grapefruit juice

Contraindications

  • History of allergy or known hypersensitivity to Mifepristone or Misoprostol
  • Confirmed or suspected ectopic pregnancy
  • Chronic adrenal failure
  • Haemorrhagic disorders or concurrent anticoagulant therapy

Side Effects

  • Nausea
  • Vomiting
  • Diarrhoea
  • Pelvic pain
  • Fainting
  • Headache
  • Dizziness

Pregnancy & Lactation

  • Mifepristone is indicated for Menstrual Regulation (MR)
  • Mifepristone effects on infants are unknown
  • Misoprostol should not be administered to nursing mothers

Precautions & Warnings

  • Combination of Mifepristone & Misoprostol should not be given to anyone else
  • Intra Uterine Device [IUD] should be removed before treatment with Mifepristone begins

Use in Special Populations

  • Patients with hepatic disease should receive a decreased dose of Misoprostol
  • No routine dosage adjustment is recommended in older patients or patients with renal impairment

Overdose Effects

  • Signs of adrenal failure in case of massive Mifepristone overdose
  • Symptoms like sedation, tremor, convulsions, and dyspnea may indicate Misoprostol overdose

Therapeutic Class

  • Drugs acting on the Uterus
  • Prostaglandin analogues

Storage Conditions

  • Store in a cool and dry place, protected from light

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