Flustar 125 mg/5 ml (Powder for Suspension)

100 ml bottle: ৳ 60.00

Medicine Details

Indications

  • Treatment of skin and soft tissue infections
  • Treatment of respiratory tract infections
  • Treatment of other infections (osteomyelitis, enteritis, endocarditis, urinary tract infection, meningitis, septicaemia)
  • Prophylactic agent for major surgical procedures

Pharmacology

  • Active against Gram-positive organisms including penicillinase producing strains
  • Inhibition of bacterial cell wall formation
  • Bactericidal antibiotic
  • Resistance to hydrolysis by penicillinase
  • Gastric acid stability
  • Activity against gram-positive bacteria

Dosage

  • Oral administration for adults, children (2-10 years) and children under 2 years
  • Parenteral administration for adults/elderly and children (2-10 years) and under 2 years
  • Dosage adjustment for severe infections like osteomyelitis and endocarditis

Administration

  • Oral doses administered 1 hour before meal

Interaction

  • Concurrent use resulting in increased level of Flucloxacillin in blood

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Common gastrointestinal side effects (nausea, vomiting, diarrhoea, dyspepsia)
  • Other reported side effects (rashes, urticaria, purpura, fever, interstitial nephritis, hepatitis, cholestatic jaundice)

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • No adequate and well-controlled studies in pregnant women
  • Excretion in human milk
  • Caution in lactating mothers

Precautions & Warnings

  • Use with caution in patients with evidence of hepatic dysfunction
  • Caution in patients with allergic diathesis

Use in Special Populations

  • Reduction in dose or extension of dose interval in severe renal failure

Therapeutic Class

  • Penicillinase-resistant penicillins

Reconstitution

  • Other routes of administration in conjunction with systemic therapy
  • Intraarticular and intrapleural injection
  • Inhalation by nebuliser

Storage Conditions

  • Dry place away from light and heat
  • Keep out of reach of children

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