Lucan-R 200 mg (Capsule)

Unit Price: ৳ 25.00 (2 x 6: ৳ 300.00)
Strip Price: ৳ 150.00

Medicine Details

Indications

  • Vaginal Candidiasis
  • Oropharyngeal Candidiasis
  • Oesophageal Candidiasis
  • Tinea corporis/Tinea cruris/Tinea pedis/Other Tinea
  • Kerion
  • Pityriasis versicolor
  • Onychomycosis
  • Invasive candidal infections and cryptococcal infections (including meningitis)
  • Prevention of cryptococcal meningitis
  • Prevention of fungal infections in immunocompromised patients
  • Systemic Candidiasis and Cryptococcal infection
  • Superficial Candidiasis
  • Fungal urinary tract infections
  • Disseminated candidiasis
  • Prophylaxis for fungal infection in neutropenic cancer patients
  • Acute treatment of other systemic fungal infections such as coccidioidomycosis and histoplasmosis

Pharmacology

Triazole antifungal agent, potent inhibitor of fungal cytochrome P-450 dependent enzymes, responsible for the synthesis of ergosterol

Dosage & Administration

  • Adults
  • Children over 1 year
  • Use in Specific Population
  • Elderly patient
  • Renal Impairment

Interaction

  • Prothrombin time after warfarin administration
  • Prolongation of the serum half-life of concomitantly administered oral sulfonylureas
  • Co-administration of multiple-dose hydrochlorothiazide to healthy volunteers
  • Concomitant administration of fluconazole and phenytoin
  • Co-administration with combined oral contraceptive
  • Impact on cyclosporine concentrations
  • Effect of co-administration with food, cimetidine, antacids, or following total body irradiation for bone marrow transplantation
  • Mean plasma clearance of theophylline

Contraindications

Known hypersensitivity to Fluconazole or related triazole compounds

Side Effects

  • Nausea
  • Abdominal discomfort
  • Diarrhoea
  • Flatulence
  • Rash
  • Anaphylaxis

Pregnancy & Lactation

Adverse fetal effects seen in animals at high dose levels, not recommended in pregnancy or in women of childbearing potential unless adequate contraception is employed

Precautions & Warnings

  • Abnormalities of hepatic, renal, hematological, and other biochemical function tests
  • Hepatic necrosis
  • Exfoliative cutaneous reactions
  • Use during lactation
  • Driving/Use of machinery

Use in Special Populations

  • Use in the elderly
  • Use in renal impairment

Overdose Effects

Supportive measures, symptomatic treatment, gastric lavage, forced volume diuresis, haemodialysis

Therapeutic Class

Drugs for subcutaneous and mycoses

Storage Conditions

Dry place away from light and heat, keep out of the reach of children

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