Rolac 60 mg/2 ml (IM/IV Injection)
2 ml ampoule: ৳ 95.36
Medicine Details
| Category | Details |
|---|---|
| Generic | Ketorolac tromethamine |
| Company | Renata limited |
| Also available as |
Indications
- Short-term management of moderate to severe acute post-operative pain
- Relieves pain, inflammation, and light sensitivity after ocular surgery
- Decreases eye inflammation or redness caused by seasonal allergies
Description
- Belongs to the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAID)
- Inhibits synthesis of prostaglandins
- Metabolized in the liver
- Excreted in the urine
Pharmacology
- Acts by inhibiting the cyclooxygenase enzyme system
- Demonstrates minimal anti-inflammatory effect at analgesic dose
Dosage & Administration
- Recommended tablet dose of 10 mg every 4-6 hours
- Injection used for moderate to severe acute pain management
- Different dosing regimens for various age groups
- Maximum daily dose limits for different patient populations
- Specific dosing for ophthalmic solution
Interaction
- NSAIDs or aspirin increase side effects of Rolac
- Anti-coagulants enhance anti-coagulant effect
- Beta Blockers reduce anti-hypertensive effect
- ACE Inhibitors increase risk of renal impairment
- Methotrexate enhances its toxicity
Contraindications
- Hypersensitivity to the drug or other NSAIDs
- Not for use in children under 16 years
- Contraindicated as prophylactic analgesic before surgery
Side Effects
- Nausea
- Vomiting
- Gastro-intestinal bleeding
- Peptic ulcer
- Pancreatitis
- Anxiety
- Drowsiness
- Headache
- Excessive thirst
- Fatigue
- Bradycardia
- Hypertension
- Palpitation
- Chest pain
- Infertility in female
- Pulmonary edema
Pregnancy & Lactation
- FDA Pregnancy category C
- Avoid in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Caution in patients over 65 years
- Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, or liver dysfunction
- Special precautions for ophthalmic solution use
Therapeutic Class
- Drugs used for Rheumatoid Arthritis
- Non-Opioid Analgesics
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children