Rolac 60 mg/2 ml (IM/IV Injection)

2 ml ampoule: ৳ 95.36

Medicine Details

Category	Details
Generic	Ketorolac tromethamine
Company	Renata limited
Also available as	Rolac 10 mg tablet Rolac 10 mg injection Rolac 30 mg injection Rolac mdt 10 mg tablet Rolac ns 1575 mg nasal spray

Indications

Short-term management of moderate to severe acute post-operative pain
Relieves pain, inflammation, and light sensitivity after ocular surgery
Decreases eye inflammation or redness caused by seasonal allergies

Description

Belongs to the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAID)
Inhibits synthesis of prostaglandins
Metabolized in the liver
Excreted in the urine

Pharmacology

Acts by inhibiting the cyclooxygenase enzyme system
Demonstrates minimal anti-inflammatory effect at analgesic dose

Dosage & Administration

Recommended tablet dose of 10 mg every 4-6 hours
Injection used for moderate to severe acute pain management
Different dosing regimens for various age groups
Maximum daily dose limits for different patient populations
Specific dosing for ophthalmic solution

Interaction

NSAIDs or aspirin increase side effects of Rolac
Anti-coagulants enhance anti-coagulant effect
Beta Blockers reduce anti-hypertensive effect
ACE Inhibitors increase risk of renal impairment
Methotrexate enhances its toxicity

Contraindications

Hypersensitivity to the drug or other NSAIDs
Not for use in children under 16 years
Contraindicated as prophylactic analgesic before surgery

Side Effects

Nausea
Vomiting
Gastro-intestinal bleeding
Peptic ulcer
Pancreatitis
Anxiety
Drowsiness
Headache
Excessive thirst
Fatigue
Bradycardia
Hypertension
Palpitation
Chest pain
Infertility in female
Pulmonary edema

Pregnancy & Lactation

FDA Pregnancy category C
Avoid in pregnancy and lactation unless benefits outweigh risks

Precautions & Warnings

Caution in patients over 65 years
Caution in patients with peptic ulcer, gastrointestinal bleeding, asthma, or liver dysfunction
Special precautions for ophthalmic solution use

Therapeutic Class

Drugs used for Rheumatoid Arthritis
Non-Opioid Analgesics

Storage Conditions

Keep in a dry place away from light and heat
Keep out of the reach of children

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