Diovan 320 mg (Tablet)

Unit Price: ৳ 70.00 (7 x 4: ৳ 1,960.00)
Strip Price: ৳ 280.00

Medicine Details

Title

  • Diovan (Valsartan)

Categories

  • Medicine
  • Pharmaceutical

Description

  • A medication used for hypertension, heart failure, and post-myocardial infarction patients

Dimensions

N/A

Color Options

N/A

Functions

  • Reduces blood pressure
  • Prevents hospitalizations in heart failure patients
  • Decreases mortality in post-myocardial infarction patients

Materials

Chemical compounds

Technical Specifications

  • Oral medication
  • Angiotensin receptor blocker (ARB)
  • Oral bioavailability
  • Specific angiotensin II antagonist
  • Acts on the AT1 subtype

Design Elements

N/A

Usability Features

  • Simple daily dosage
  • Suitable for elderly patients with mild to moderate renal and hepatic insufficiency

Indications

  • Hypertension
  • Heart failure
  • Post-myocardial infarction

Pharmacology

  • Blocks angiotensin II receptor
  • Dilates blood vessels
  • Reduces blood pressure without affecting pulse rate
  • Greater affinity for the AT1 receptor than for the AT2 receptor

Dosage

  • Hypertension: 80 to 160 mg once daily (up to 320 mg daily)
  • Heart Failure: 40 mg to 160 mg twice daily
  • Post-Myocardial Infarction: 20 mg to 160 mg daily

Administration

  • Should be taken on an empty stomach
  • No initial dosage adjustment required for elderly patients with mild to moderate renal and hepatic insufficiency

Interactions

  • Several compounds studied in clinical trials
  • No significant drug interactions
  • No expected metabolic induction or inhibition of cytochrome P450 system
  • Potassium sparing diuretics, potassium supplements, or salt substitutes containing potassium may increase serum potassium

Contraindications

  • Hypersensitivity to any component of the product

Side Effects

  • Headache
  • Dizziness
  • Fatigue
  • Abdominal pain
  • Cough
  • Diarrhea
  • Nausea
  • Hyperkalemia
  • Impotency
  • Reduced renal function
  • Allergic reactions
  • Dyspnea
  • Constipation
  • Back pain
  • Muscle cramps
  • Rash
  • Anxiety
  • Insomnia
  • Vertigo
  • Hypotension

Pregnancy & Lactation

  • Pregnancy: Should not be used in pregnancy (2nd and 3rd trimester)
  • Nursing mothers: Not known whether excreted in human milk. Decision should be made whether to discontinue nursing or the drug

Precautions & Warnings

  • Exercise caution in hepatic impairment including biliary obstructive disorder
  • Dosage reduction or discontinuation may be required with pre-existing renal impairment
  • Caution when initiating therapy in heart failure and post-myocardial infarction patients

Use in Special Populations

  • Pediatric use not established
  • No overall difference in efficacy or safety observed in geriatric population
  • Specific dosages for patients with hepatic impairment

Overdose Effects

  • Limited data available
  • Manifestations may include hypotension, tachycardia, and bradycardia from parasympathetic (vagal) stimulation

Therapeutic Class

  • Angiotensin-ll receptor blocker

Storage Conditions

Store between 15-30°C, protect from moisture and heat

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