Serotal 10 mg (Tablet)

Unit Price: ৳ 10.00 (2 x 10: ৳ 200.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Escitalopram oxalate
Company Globe pharmaceuticals ltd
Also available as

Title

  • Serotal

Categories

  • Antidepressant
  • Selective Serotonin Reuptake Inhibitor (SSRI)

Description

  • Indications:
    • Treatment of major depressive episodes
    • Treatment of panic disorder with or without agoraphobia
    • Treatment of social anxiety disorder (social phobia)
    • Treatment of generalised anxiety disorder
    • Treatment of obsessive-compulsive disorder
  • Pharmacology:
    • SSRI
    • Selective serotonin reuptake inhibitor
    • Pure S-enantiomer of citalopram
  • Dosage:
    • Maximum daily dose of 20 mg
    • Usual dosage of 10 mg once daily for major depressive episodes
    • Initial dose of 5 mg recommended for panic disorder
    • Social anxiety disorder usual dosage of 10 mg once daily
    • Generalised anxiety disorder initial dosage of 10 mg once daily
    • Obsessive-Compulsive Disorder initial dosage of 10 mg once daily
  • Administration:
    • Administered once daily, morning or evening
    • May be taken with or without food
  • Interaction:
    • Do not start SSRI until 2 weeks after stopping an MAOI
    • Conversely, MAOI should not be started until at least a week after stopping an SSRI
  • Contraindications:
    • Hypersensitivity to Escitalopram or Citalopram
    • Concomitant use of escitalopram in patients taking monoamine oxidase/pimozide
  • Side Effects:
    • Less sedating than tricyclic antidepressants
    • Fewer antimuscarinic and cardiotoxic effects than tricyclic antidepressants
    • Gastrointestinal effects include nausea, vomiting, dyspepsia, abdominal pain, diarrhea, constipation
  • Pregnancy & Lactation:
    • Carefully consider potential risks and benefits of treatment during the third trimester
    • Excreted in human breast milk
  • Precautions & Warnings:
    • Use with caution in patients with epilepsy
    • Avoid if poorly controlled epilepsy
    • Discontinue if convulsions develop
    • Use with caution in patients with history of mania, cardiac disease, diabetes mellitus
  • Use in Special Populations:
    • Elderly patients (>65 years of age) initial dose of 5 mg once daily
    • Children and adolescents (<18 years) should not use Serotal
    • No dosage adjustment necessary in patients with mild or moderate renal impairment
    • Extra careful dose titration advised in patients with severely reduced hepatic function
    • For poor metabolizers of CYP2C19, an initial dose of 5 mg daily is recommended
  • Overdose Effects:
    • Symptoms include dizziness, tremor, agitation, serotonin syndrome, convulsion, coma, nausea, vomiting, hypotension, tachycardia, QT interval prolongation, arrhythmia, electrolyte/fluid balance conditions
  • Therapeutic Class:
    • SSRIs & related anti-depressant drugs
  • Storage Conditions:
    • Store below 30°C temperature
    • Protect from light & moisture
    • Keep out of the reach of children

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