Taxotere 80 mg/vial (IV Infusion)
80 mg vial: ৳ 36,450.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Docetaxel trihydrate |
| Company | Synovia pharma plc |
| Also available as |
Title
- Taxotere (Docetaxel) Injection
Categories
- Chemotherapy
- Antineoplastic Agent
- Cytotoxic Chemotherapy
Description
- Microtubule Inhibitor
- Indicated for Breast Cancer, Non-small Cell Lung Cancer, Prostate Cancer, Gastric Adenocarcinoma, Squamous Cell Carcinoma of the Head and Neck
- Acts by Disrupting Microtubular Network in Cells
- Promotes Assembly of Tubulin into Stable Microtubules
- Inhibits Mitosis in Cells
- Administered Intravenously over 1 Hour Every 3 Weeks
- Premedicate with Oral Corticosteroids
- CYP3A4 Substrate
- Contraindicated in Neutrophil Counts <1500 cells/mm^3
Dosage & Administration
- Administer in Facility Equipped to Manage Complications
- Use Only a 21 Gauge Needle to Withdraw Docetaxel from the Vial
- Dosage Varies Based on Cancer Type
- Adjust Dose as Needed
- Specific Dosage Instructions for Breast Cancer, Non-small Cell Lung Cancer, Prostate Cancer, Gastric Adenocarcinoma, Squamous Cell Carcinoma of the Head and Neck
Interaction
- Metabolism may be Modified by Concomitant Administration of Compounds
Contraindications
- Neutrophil Counts <1500 cells/mm^3
- History of Severe Hypersensitivity Reactions to Docetaxel or Polysorbate 80
Side Effects
- Infections
- Neutropenia
- Anemia
- Febrile Neutropenia
- Hypersensitivity
- Thrombocytopenia
- Neuropathy
- Dysgeusia
- Dyspnea
- Constipation
- Anorexia
- Nail Disorders
- Fluid Retention
- Asthenia
- Pain
- Nausea
- Diarrhea
- Vomiting
- Mucositis
- Alopecia
- Skin Reactions
- Myalgia
Pregnancy & Lactation
- Can Cause Fetal Harm in Pregnant Women
Precautions & Warnings
- Should be Administered Under Supervision of Experienced Physician
- Higher Risk in Patients with Hepatic Impairment
- Closely Monitor Patients for Severe Hypersensitivity Reactions
- Acute Myeloid Leukemia May Occur
Overdose Effects
- No Known Antidote for Docetaxel Overdose
- Bone Marrow Suppression
- Peripheral Neurotoxicity
- Mucositis
- Therapeutic G-CSF as Soon as Possible After Overdose
- Other Appropriate Symptomatic Measures as Needed
Therapeutic Class
- Cytotoxic Chemotherapy
Storage Conditions
- Store Between 2°C and 25°C
- Protected from Light
- Freezing Does Not Adversely Affect the Product